包头医学院学报
包頭醫學院學報
포두의학원학보
JOURNAL OF BAOTOU MEDICAL COLLEGE
2014年
6期
38-40
,共3页
脑梗死%胱抑素C%同型半胱氨酸%超敏C反应蛋白
腦梗死%胱抑素C%同型半胱氨痠%超敏C反應蛋白
뇌경사%광억소C%동형반광안산%초민C반응단백
Cerebral infarction%Cyst-C%Hcy%hs-CRP
目的：探讨血清胱抑素C（cystatin C ，CysC）、同型半胱氨酸（homocysteine ，Hcy）、超敏C反应蛋白（high sensitivity Creactive protein ，hsCRP）水平与不同类型急性脑梗死的关系。方法：选择神经内科收治的100例急性脑梗死患者为观察组，并按照TOAST分型标准进行病因分型；选择80例非脑卒中病例为对照组，分别测定和比较两组患者血清CysC、Hcy以及hsCRP的水平。结果：脑梗死组患者血清CysC、Hcy、hsCRP水平高于对照组（ P＜0．05），经Logistic回归分析三者均为脑梗死的危险因素（ OR值分别为1．989、2．013、1．601）；观察组中大动脉粥样硬化型（L A A ）、小动脉闭塞型（SAA）患者血清CysC、Hcy、hsCRP水平均高于对照组（ P＜0．05），其中以LAA型增高显著（ P＜0．01）。结论：血清CysC、Hcy和hsCRP水平升高均与脑梗死密切相关，可能是脑梗死的危险因素，但不同亚型脑梗死可能有不同病因。
目的：探討血清胱抑素C（cystatin C ，CysC）、同型半胱氨痠（homocysteine ，Hcy）、超敏C反應蛋白（high sensitivity Creactive protein ，hsCRP）水平與不同類型急性腦梗死的關繫。方法：選擇神經內科收治的100例急性腦梗死患者為觀察組，併按照TOAST分型標準進行病因分型；選擇80例非腦卒中病例為對照組，分彆測定和比較兩組患者血清CysC、Hcy以及hsCRP的水平。結果：腦梗死組患者血清CysC、Hcy、hsCRP水平高于對照組（ P＜0．05），經Logistic迴歸分析三者均為腦梗死的危險因素（ OR值分彆為1．989、2．013、1．601）；觀察組中大動脈粥樣硬化型（L A A ）、小動脈閉塞型（SAA）患者血清CysC、Hcy、hsCRP水平均高于對照組（ P＜0．05），其中以LAA型增高顯著（ P＜0．01）。結論：血清CysC、Hcy和hsCRP水平升高均與腦梗死密切相關，可能是腦梗死的危險因素，但不同亞型腦梗死可能有不同病因。
목적：탐토혈청광억소C（cystatin C ，CysC）、동형반광안산（homocysteine ，Hcy）、초민C반응단백（high sensitivity Creactive protein ，hsCRP）수평여불동류형급성뇌경사적관계。방법：선택신경내과수치적100례급성뇌경사환자위관찰조，병안조TOAST분형표준진행병인분형；선택80례비뇌졸중병례위대조조，분별측정화비교량조환자혈청CysC、Hcy이급hsCRP적수평。결과：뇌경사조환자혈청CysC、Hcy、hsCRP수평고우대조조（ P＜0．05），경Logistic회귀분석삼자균위뇌경사적위험인소（ OR치분별위1．989、2．013、1．601）；관찰조중대동맥죽양경화형（L A A ）、소동맥폐새형（SAA）환자혈청CysC、Hcy、hsCRP수평균고우대조조（ P＜0．05），기중이LAA형증고현저（ P＜0．01）。결론：혈청CysC、Hcy화hsCRP수평승고균여뇌경사밀절상관，가능시뇌경사적위험인소，단불동아형뇌경사가능유불동병인。
Objective :To investigate the relationship of serum cystatin C (CysC) ,homocysteine (Hcy)and high sen_sitivity C reactive protein (hs-CRP) with different types of Cerebral Infarction .Methods :100 cases of acute cerebral in_farction hospitalized in our department of Neurology were selected to be the cerebral infarction group ,with etiological typ_ing performed by TOAST criteria .80 cases of non -cerebrovascular disease were enrolled as a control group .The con_centration of CysC ,Hcy and hs-CRP in the blood serum of the two groups was determined and compared to find if there is any difference between the two groups .ResuIts :The level of CysC ,Hcy and hs-CRP in the cerebral infarction group was significantly higher than that in the control group( P<0 .05) ,with Logistic regression analysis revealing that CysC , Hcy and hs-CRP were the risk factors for cerebral infarction (OR:1 .989 ,2 .013 and 1 .601) .The level of serum CysC , Hcy and hs -CRP of LAA and SAA patients in the cerebral infarction group was higher than that in the control group ( P<0 .05) ,most significantly higher in LAA patients( P<0 .01) .Conclusion :The level of CysC ,Hcy and hs-CRP ,the possible risk factors ,were closely related to acute cerebral infarction .There may be various etiological factors for differ_ent subtypes of cerebral infarction ,however .
