广州化工
廣州化工
엄주화공
GUANGZHOU CHEMICAL INDUSTRY AND TECHNOLOGY
2014年
23期
106-107
,共2页
乙酰阿魏酸乙酯%酯化反应%DCC/DMAP催化
乙酰阿魏痠乙酯%酯化反應%DCC/DMAP催化
을선아위산을지%지화반응%DCC/DMAP최화
ethyl ester of acetyl ferulic acid%esterification reaction%DCC/DMAP catalyze
以4－羟基－3－甲氧基苯甲醛为起始原料，合成了中间产物乙酰阿魏酸，再以N，N－二环己基碳二亚胺（ DCC）和4－二甲胺基吡啶（ DMAP）为催化剂，通过酯化反应制备了乙酰阿魏酸乙酯，各步产物通过红外光谱、质谱和元素分析对其结构进行表征确认。实验结果表明：在室温下，催化剂用量为乙酰阿魏酸用量的3％，反应时间为4 h的条件下，产率达到75％，为最优条件。
以4－羥基－3－甲氧基苯甲醛為起始原料，閤成瞭中間產物乙酰阿魏痠，再以N，N－二環己基碳二亞胺（ DCC）和4－二甲胺基吡啶（ DMAP）為催化劑，通過酯化反應製備瞭乙酰阿魏痠乙酯，各步產物通過紅外光譜、質譜和元素分析對其結構進行錶徵確認。實驗結果錶明：在室溫下，催化劑用量為乙酰阿魏痠用量的3％，反應時間為4 h的條件下，產率達到75％，為最優條件。
이4－간기－3－갑양기분갑철위기시원료，합성료중간산물을선아위산，재이N，N－이배기기탄이아알（ DCC）화4－이갑알기필정（ DMAP）위최화제，통과지화반응제비료을선아위산을지，각보산물통과홍외광보、질보화원소분석대기결구진행표정학인。실험결과표명：재실온하，최화제용량위을선아위산용량적3％，반응시간위4 h적조건하，산솔체도75％，위최우조건。
Intermediate 3-( 4-acetoxy-3-methoxyphenyl ) acrylic acid was synthesized by 4-hydroxy-3-methoxybenzaldehyde, with dicyclohexyl carbodiimide ( DCC) and 4-dime-thylamino pyridine ( DMAP) as catalyst. Ethyl ester of acetyl ferulic acid was synthesized by esterification reaction.Target product was characterized by IR, elemental analysis and MS.The experimental results showed at room temperature, the amount of catalyst accounts for 3%of the acetyl ferulic acid, and reaction 4 h was the best condition.
