CAJ | 학술논문

磷脂酶A2（ PLA2）是一类能催化脂蛋白和膜甘油磷脂水解的酶族，主要包括分泌型磷脂酶A2（sPLA2）、胞浆型磷脂酶A2（cPLA2）、钙离子非依赖型磷脂酶A2（iPLA2）和脂蛋白相关磷脂酶A2（Lp-PLA2）。sPLA2， cPLA2， iPLA2和Lp-PLA2与多种疾病密切相关，尤其在心血管疾病中的研究成为近年来的热点。本文就近几年PLA2在心血管疾病动物中的实验研究作一综述。
린지매A2（ PLA2）시일류능최화지단백화막감유린지수해적매족，주요포괄분비형린지매A2（sPLA2）、포장형린지매A2（cPLA2）、개리자비의뢰형린지매A2（iPLA2）화지단백상관린지매A2（Lp-PLA2）。sPLA2， cPLA2， iPLA2화Lp-PLA2여다충질병밀절상관，우기재심혈관질병중적연구성위근년래적열점。본문취근궤년PLA2재심혈관질병동물중적실험연구작일종술。
Phospholipase A2(PLA2)is a class of enzymes with the ability to catalyze hydrolysis of lipoproteins and glycerophospholipid in the membrane, mainly including secreted PLA2 ( sPLA2 ) , cytosolic PLA2 ( cPLA2 ) , Ca2+-independent PLA2 ( iPLA2 ) and lipoprotein-associated phospholipase A2 ( Lp-PLA2 ) .They are closely related to many diseases.The studies of the role of PLA2 in cardiovascular diseases have been a hot topic in recent years.This paper focuses on the recent advances in research on the effects of PLA2 on cardiovascular diseases in animal experiments.