CAJ | 학술논문

目的：通过对比脑转移瘤放疗前后的磁敏感加权成像(SWI)及增强 T1 WI 的表现来评价 SWI 在脑转移瘤放疗前后的应用价值。方法38例肺癌脑转移患者放疗前及放疗后2~3个月分别行 SWI 检查及增强 T1 WI 检查,观察2种方法对转移瘤的显示情况并评分(0~3分,0分代表未显示,1分代表显示不佳,2分代表可判断,3分代表清楚显示)。结果放疗前,SWI 检出转移瘤161个,并能清楚显示脑转移瘤内肿瘤血管影,平均评分为2.73±0.05；增强 T1 WI 检出转移瘤161个,平均评分为1.93±0.04；经配对样本 t 检验,SWI 对肿瘤显示评分大于增强 T1 WI(P <0.05)。放疗后,SWI 检出转移瘤89个,平均评分1.47±0.11,增强T1 WI 检出140个,平均评分1.80±0.07；增强 T1 WI 显示肿瘤评分大于 SWI(P <0.05)。结论SWI 对放疗前转移瘤病灶显示比增强 T1 WI 优越,SWI 还可以清楚显示脑转移瘤内肿瘤血管；SWI 对放疗后转移瘤病灶显示不如增强 T1 WI,在放疗后治疗效果评估方面 SWI 存在一定的应用价值,为疗效的评价增加了一种新的手段。
목적：통과대비뇌전이류방료전후적자민감가권성상(SWI)급증강 T1 WI 적표현래평개 SWI 재뇌전이류방료전후적응용개치。방법38례폐암뇌전이환자방료전급방료후2~3개월분별행 SWI 검사급증강 T1 WI 검사,관찰2충방법대전이류적현시정황병평분(0~3분,0분대표미현시,1분대표현시불가,2분대표가판단,3분대표청초현시)。결과방료전,SWI 검출전이류161개,병능청초현시뇌전이류내종류혈관영,평균평분위2.73±0.05；증강 T1 WI 검출전이류161개,평균평분위1.93±0.04；경배대양본 t 검험,SWI 대종류현시평분대우증강 T1 WI(P <0.05)。방료후,SWI 검출전이류89개,평균평분1.47±0.11,증강T1 WI 검출140개,평균평분1.80±0.07；증강 T1 WI 현시종류평분대우 SWI(P <0.05)。결론SWI 대방료전전이류병조현시비증강 T1 WI 우월,SWI 환가이청초현시뇌전이류내종류혈관；SWI 대방료후전이류병조현시불여증강 T1 WI,재방료후치료효과평고방면 SWI 존재일정적응용개치,위료효적평개증가료일충신적수단。
Objective To evaluate the value of susceptibility-weighted imaging (SWI)sequence in the diagnosis of metastatic en-cephaloma pre and after radiotherapy by comparing the appearance of the SWI and contrast-enhanced T1-weighted imaging(T1 WI). Methods Thirty-eight lung cancer patients with brain metastases underwent SWI and contrast-enhanced T1-weighted imaging re-spectively before and 2-3 months after radiotherapy.Evaluated the two methods by score(the score ranged from 0-3,0 represen-ted no showing,1 represented not showing clearly,2 represented could judging,3 represented showing obviously).Results Before radiotherapy,SWI detected 1 61 lesions of metastases and could obviously show tumor vascular in brain metastases (mean score 2.73±0.05).Contrast-enhanced T1 WI detected 1 61 lesions(mean score 1.93±0.04 ).SWI showed significantly higher score than enhanced T1 WI(P <0.05)through paired sample t test.After radiotherapy,SWI found 98 lesions (mean score 1.47±0.1 1 )and en-hanced T1 WI found 140 lesions (mean score 1.80±0.07),enhanced T1 WI had significantly higher score than SWI(P <0.05).Con-clusion SWI is superior to contrast-enhanced T1 WI to show the metastases before radiotherapy and can show tumor vascular in brain metastases obviously.SWI is inferior to enhanced T1 WI after radiotherapy.It has some value and may provide a new method for evaluating effects of radiotherapy.