CAJ | 학술논문

目的探讨孕产妇甲型H1N1流感病例的临床特点。方法收集我院收治的12例孕产妇甲型H1N1流感确诊病例，常规检测血常规、血气分析、肝肾功能及心肌酶学、淋巴细胞亚群、胸片及胸部CT。采用奥司他韦、氧疗及呼吸支持、抗感染、对症支持等综合治疗。结果患者以发热、咳嗽、咳痰、流涕、咽痛为主要症状，重症可出现胸憋气紧；91.7%的患者白细胞正常或增高，9例患者肺部病灶表现多样，进展快，2例发展为急性呼吸窘迫综合征（ARDS）；部分病例出现多脏器损害表现；奥司他韦、有效氧疗及机械通气、抗感染及支持治疗有效。结论孕产妇甲型H1N1流感患者白细胞正常或增高；以肺部病变为主，伴有多脏器功能异常表现；中晚期孕妇及产妇甲型H1N1流感易发展为重症；孕产妇甲型H1N1流感易合并细菌感染，建议早期应用抗生素治疗。
목적탐토잉산부갑형H1N1류감병례적림상특점。방법수집아원수치적12례잉산부갑형H1N1류감학진병례，상규검측혈상규、혈기분석、간신공능급심기매학、림파세포아군、흉편급흉부CT。채용오사타위、양료급호흡지지、항감염、대증지지등종합치료。결과환자이발열、해수、해담、류체、인통위주요증상，중증가출현흉별기긴；91.7%적환자백세포정상혹증고，9례환자폐부병조표현다양，진전쾌，2례발전위급성호흡군박종합정（ARDS）；부분병례출현다장기손해표현；오사타위、유효양료급궤계통기、항감염급지지치료유효。결론잉산부갑형H1N1류감환자백세포정상혹증고；이폐부병변위주，반유다장기공능이상표현；중만기잉부급산부갑형H1N1류감역발전위중증；잉산부갑형H1N1류감역합병세균감염，건의조기응용항생소치료。
Objective To study the clinical features of cases of new influenza A (H1N1) in pregnant and postpartum women. Methods We collected 12 confirmed cases of new influenza A (H1N1) in pregnant and postpartum women hospitalized at The Forth People's Hospital of Taiyuan .The lab tests, including blood routine, blood gas analysis, liver and renal function tests, myocardium enzymology , lymphocyte subpopulations, chest radiograph and computed tomogram were analyzed. The cases were cured with combined therapy :oseltamivir, oxygen therapy, anti-infection or symptomatic treatment. Results Fever , cough , expectoration , nasal discharge and sore throat were the principal symptoms , severe patients show oppression in thest and breath shortness. The ratios of normal and increased WBC were 91.7%.9 cases' chest radiograph or computed tomogram were diverse and the disease developed quickly, two patients grew ARDS. Some cases showed the impairment of multiple organs.Oseltamivir, oxygen therapy , mechanical ventilation , anti-infection and supporting therapy were effective for improvement of this patient. Conclusion The WBC of cases of new influenza A (H1N1) in pregnant and postpartum women was normal or increased. The cases show mainly pulmonary lesion with multi-organ dysfunction.The women in the Second and Third Trimester and the postpartum women suffer more likely develop severe cases .The cases of new influenza A (H1N1) in pregnant and postpartum women combined more likely with bacterial infection and were suggested to treat with antibiotics in early stage.