CAJ | 학술논문

目的：探讨不典型脑后部可逆性脑病综合征(PRES)的临床表现及MRI特点。方法收集我院5例确诊为不典型PRES患者的临床资料，分析其临床及MRI图像特点。结果5例不典型PRES患者有男性1例，女性4例，其相关病因为：原发性高血压(1例)、剖宫产术后高血压(3例)以及肾功能不全高血压(1例)。发病时患者的收缩压高值平均为188mmHg，临床症状主要为头痛。患者恢复时间为2-14d。头颅MRI：病变主要发生于额叶(1例)，脑干(3例)，基底节区(1例)，3例伴其他部位病灶，其中仅1例伴右侧顶枕叶病灶。T1WI病变区呈等或略低信号；FLAIR及T2WI病变区呈高信号；大部分(4例)DWI病变区呈等或低信号，ADC呈高信号，小部分(1例)DWI病变区呈高信号，ADC呈等信号。患者于治疗后2-4周复查MRI，病变区均有不同程度的缩小或消失。结论不典型PRES临床表现亦不典型，但是结合MRI表现还是有其特征性，影像诊断医生应当提高对其认识，尤其是对有相关基础疾病的患者，临床症状与MRI表现明显不符，需要考虑本病的可能。
목적：탐토불전형뇌후부가역성뇌병종합정(PRES)적림상표현급MRI특점。방법수집아원5례학진위불전형PRES환자적림상자료，분석기림상급MRI도상특점。결과5례불전형PRES환자유남성1례，녀성4례，기상관병인위：원발성고혈압(1례)、부궁산술후고혈압(3례)이급신공능불전고혈압(1례)。발병시환자적수축압고치평균위188mmHg，림상증상주요위두통。환자회복시간위2-14d。두로MRI：병변주요발생우액협(1례)，뇌간(3례)，기저절구(1례)，3례반기타부위병조，기중부1례반우측정침협병조。T1WI병변구정등혹략저신호；FLAIR급T2WI병변구정고신호；대부분(4례)DWI병변구정등혹저신호，ADC정고신호，소부분(1례)DWI병변구정고신호，ADC정등신호。환자우치료후2-4주복사MRI，병변구균유불동정도적축소혹소실。결론불전형PRES림상표현역불전형，단시결합MRI표현환시유기특정성，영상진단의생응당제고대기인식，우기시대유상관기출질병적환자，림상증상여MRI표현명현불부，수요고필본병적가능。
Objective To investigate the clinical manifestations and features of MRI of the atypical posterior reversible encephalopathy syndromes (PRES). Methods The clinical data of 5 patients with atypical PRES in our hospital were collected, analyzed the clinical manifestations and the features of MRI images. Results There are 1 male and 4 female in the 5 atypical PRES patients. Related factors included essential hypertension (1 cases), cesarean section postoperative hypertension (3 cases) and renal insufficiency hypertension (1 cases). Mean peak systolic blood pressure at presentation was 188 mmHg. The main clinical symptoms were headache. Patients recovered in 2-14d. Head MRI: Lesions occurred mainly in the frontal lobe (1 cases), brain stem (3 cases) and basal ganglia (1 cases).3 cases of them with other lesions and only 1 cases with right parietal occipital lobe lesion.T1WI lesions showed equal or slightly low signal. FLAIR and T2WI lesions showed high signal. Most (4 cases) DWI lesions showed equal or low signal and ADC showed high signal. Small (1 cases) DWI lesion showed high signal and ADC showed equal signal. The lesions had different degrees of reduction or disappearance when patients review MRI after 2-4 weeks of treatment. Conclusion The clinical manifestations of atypical PRES are not typical, but still have characteristics with MRI examination. Imaging diagnosis of doctors should improve the knowledge, especially for the underlying disease. Clinical symptoms and MRI findings were inconsistent, need to consider the possibility of this disease.