CAJ | 학술논문

目的：分析6例胆管囊腺瘤的临床特点，提高对胆管囊腺瘤的认识。方法回顾性分析中山大学孙逸仙纪念医院自2009年9月到2014年9月收治的6例胆管囊腺瘤患者的临床表现、影像特点及手术治疗结局情况。结果6例患者均为女性，年龄28～46岁。就诊主诉为：上腹痛占50％（3／6），无症状体检发现33．3％（2／6），黄疸、发热占13．7％（1／6）。发病至就诊时间3天～16年。除黄疸、发热患者肝功能异常外，其余患者术前肝功能无异常。肿瘤指标均无异常。术前B超、CT均未能作出准确定性诊断，仅2例术前经MR检查准确诊断。全部患者均行外科手术完整切除病灶，术后无明显手术并发症。术后随访3月～46月无复发。结论胆管囊腺瘤发病稀少，病因未明，好发于中年女性，临床症状轻，实验室及影像学检查诊断本病有一定困难，目前仍然依赖于病理。本病手术效果良好，完整切除病灶对本病预后极为重要。
목적：분석6례담관낭선류적림상특점，제고대담관낭선류적인식。방법회고성분석중산대학손일선기념의원자2009년9월도2014년9월수치적6례담관낭선류환자적림상표현、영상특점급수술치료결국정황。결과6례환자균위녀성，년령28～46세。취진주소위：상복통점50％（3／6），무증상체검발현33．3％（2／6），황달、발열점13．7％（1／6）。발병지취진시간3천～16년。제황달、발열환자간공능이상외，기여환자술전간공능무이상。종류지표균무이상。술전B초、CT균미능작출준학정성진단，부2례술전경MR검사준학진단。전부환자균행외과수술완정절제병조，술후무명현수술병발증。술후수방3월～46월무복발。결론담관낭선류발병희소，병인미명，호발우중년녀성，림상증상경，실험실급영상학검사진단본병유일정곤난，목전잉연의뢰우병리。본병수술효과량호，완정절제병조대본병예후겁위중요。
Objective To explore the clinical characteristics of biliary cystadenoma (BCA) and review literature. Methods Six cases with BCA were admitted to Sun Yat-sen Memorial Hospital from September 2009 to September 2014 and underwent surgical procedure. The Clinical manifestation , imaging feature and surgical results from six BCAs were analyzed retrospectively. Results All 6 patients were female, and aged from 28 to 46 years old. Chief complains were upper abdominal pain (50%, 3/6), asymptomatic examination found (33.3%,2/6) and jaundice with fever (13.7%,1/6). Course of disease ranged from 3 days to 16 years. No abnormal preoperative liver functions were found except the cases with jaundice and fever,and tumor markers of all the patients showed no abnormality. Preoperative B ultrasound,and CT examinations failed to make an accurate diagnosis, only two case were confirmed by MR. All patients underwent complete resection of the whole lesion without complication or recurrence in a follow-up duration of 3-46 months. Conclusion The incidence of BCA is rare and its cause is unclear. It occurs predominantly in middle-aged women with mild clinical symptoms and it is hard to make an accurate preoperative diagnosis by laboratory and imaging examinations. The final diagnosis still depends on pathological examination. Complete removal of the whole lesion is essential for BCA.