医学分子生物学杂志
醫學分子生物學雜誌
의학분자생물학잡지
FOREIGN MEDICAL SCIENCES
2014年
6期
311-317
,共7页
尹太郎%夏曦%穆杨%李赛姣%解迪%张怡%丁锦丽%邹宇洁%徐望明%杨菁
尹太郎%夏晞%穆楊%李賽姣%解迪%張怡%丁錦麗%鄒宇潔%徐望明%楊菁
윤태랑%하희%목양%리새교%해적%장이%정금려%추우길%서망명%양정
体外受精-胚胎移植%生化妊娠%危险因素%Logistic 回归
體外受精-胚胎移植%生化妊娠%危險因素%Logistic 迴歸
체외수정-배태이식%생화임신%위험인소%Logistic 회귀
in vitro fertilization and embryo transfer%biochemical pregnancy%influential fac-tor%logistic regression
目的：通过分析 IVF-ET 治疗后终止于生化妊娠与发展为临床妊娠两种结局患者之间的各相关因素，试图探讨生化妊娠发生的影响因素。方法对55例生化妊娠﹑100例同期临床妊娠患者的临床资料进行回顾性分析，采用非条件 Logistic 回归方法比较两组间的各暴露因素。结果男方年龄﹑原发/继发不孕﹑是否有自然流产史﹑降调方案﹑基础窦卵泡数﹑受精率是生化妊娠的显著影响因素(P ﹤0.05)，是否有自然流产史，基础窦卵泡数是生化妊娠的独立影响因素。结论 IVF-ET 治疗中生化妊娠的发生受年龄﹑卵巢储备功能﹑超促排卵方案﹑是否有自然流产史等多因素影响的。
目的：通過分析 IVF-ET 治療後終止于生化妊娠與髮展為臨床妊娠兩種結跼患者之間的各相關因素，試圖探討生化妊娠髮生的影響因素。方法對55例生化妊娠﹑100例同期臨床妊娠患者的臨床資料進行迴顧性分析，採用非條件 Logistic 迴歸方法比較兩組間的各暴露因素。結果男方年齡﹑原髮/繼髮不孕﹑是否有自然流產史﹑降調方案﹑基礎竇卵泡數﹑受精率是生化妊娠的顯著影響因素(P ﹤0.05)，是否有自然流產史，基礎竇卵泡數是生化妊娠的獨立影響因素。結論 IVF-ET 治療中生化妊娠的髮生受年齡﹑卵巢儲備功能﹑超促排卵方案﹑是否有自然流產史等多因素影響的。
목적：통과분석 IVF-ET 치료후종지우생화임신여발전위림상임신량충결국환자지간적각상관인소，시도탐토생화임신발생적영향인소。방법대55례생화임신﹑100례동기림상임신환자적림상자료진행회고성분석，채용비조건 Logistic 회귀방법비교량조간적각폭로인소。결과남방년령﹑원발/계발불잉﹑시부유자연유산사﹑강조방안﹑기출두란포수﹑수정솔시생화임신적현저영향인소(P ﹤0.05)，시부유자연유산사，기출두란포수시생화임신적독립영향인소。결론 IVF-ET 치료중생화임신적발생수년령﹑란소저비공능﹑초촉배란방안﹑시부유자연유산사등다인소영향적。
Objective To analyze various relevant factors that contribute to the development of the biochemical pregnancy or the clinical pregnancy after the IVF-ET in order to identify the factors related to the biochemical pregnancy. Methods Clinical data on 55 cycles of biochemical pregnan-cies and 100 cycles of clinical pregnancies were analyzed retrospectively. Step-wise logistic regression analysis was done to compare exposed influence factors between the two groups. Results Male age, primary or secondary infertility, use of gonadotropin-releasing hormone agonist in assisted reproduc-tion cycles, ratio of fertilization, basic antral follicle count (AFC) and spontaneous abortion were the significant influence factors for biochemical pregnancies ( P ﹤ 0. 05) . Furthermore, it was found that the basic AFC and the history of spontaneous abortion were the independent factors for bi-ochemical pregnancy. Conclusion The occurrence of biochemical pregnancy in the IVF-ET treat-ment is affected by the age, ovarian reserve, ovarian hyperstimulation program and history of spon-taneous abortion etc.
