CAJ | 학술논문

目的：探讨剪切波弹性成像杨氏模量值与桥本甲状腺炎（H T ）不同临床表现的相关性。方法将收集的86例临床确诊为HT的患者按照甲状腺功能分成甲亢组、甲功正常组、亚临床甲减组和临床甲减组，应用超声剪切波弹性成像技术，对各组进行超声剪切波弹性量化检测，用方差分析比较各组 HT 患者甲状腺组织剪切波模量值之间的关系。结果甲亢组、甲功正常组、亚临床甲减组和临床甲减组的 HT 患者甲状腺组织剪切波弹性模量值依次增大，分别为（15．543±4．319）kPa、（20．083±5．444）kPa、（26．682±5．676）kPa、（29．210±8．848）kPa ，组间差异有统计学意义（ F ＝14．925，P ＜0．01）。HT甲亢组剪切波弹性模量值低于 HT甲功正常组、HT亚临床甲减组、HT临床甲减组，差异均有统计学意义（ P均＜0．05）。HT甲功正常组剪切波弹性模量值低于 HT亚临床甲减组、HT 临床甲减组，差异有统计学意义（ P均＜0．05）。结论剪切波弹性成像杨氏模量值与桥本甲状腺炎不同时期的临床表现有一定相关性，可为 HT的治疗提供一定的参考信息。
목적：탐토전절파탄성성상양씨모량치여교본갑상선염（H T ）불동림상표현적상관성。방법장수집적86례림상학진위HT적환자안조갑상선공능분성갑항조、갑공정상조、아림상갑감조화림상갑감조，응용초성전절파탄성성상기술，대각조진행초성전절파탄성양화검측，용방차분석비교각조 HT 환자갑상선조직전절파모량치지간적관계。결과갑항조、갑공정상조、아림상갑감조화림상갑감조적 HT 환자갑상선조직전절파탄성모량치의차증대，분별위（15．543±4．319）kPa、（20．083±5．444）kPa、（26．682±5．676）kPa、（29．210±8．848）kPa ，조간차이유통계학의의（ F ＝14．925，P ＜0．01）。HT갑항조전절파탄성모량치저우 HT갑공정상조、HT아림상갑감조、HT림상갑감조，차이균유통계학의의（ P균＜0．05）。HT갑공정상조전절파탄성모량치저우 HT아림상갑감조、HT 림상갑감조，차이유통계학의의（ P균＜0．05）。결론전절파탄성성상양씨모량치여교본갑상선염불동시기적림상표현유일정상관성，가위 HT적치료제공일정적삼고신식。
Objective To investigate shear wave elastography Young's modulus and correlation Hashimoto's thyroiditis (HT) with different clinical manifestations .Methods We divided the 86 cases ,which were clinically diagnosed with HT according to the thyroid function ,into the hyperthyroidism group ,the normal thyroid function group ,the subclinical hy‐pothyroidism group ,and the clinical hypothyroidism group .Using ultrasonic shear wave elastography ,we tested each group to get a elastic modulus .Using analysis of variance ,we compared the relationship of each group’s elastic modulus result .Results The elastic modulus of each group increased successively in hyperthyroidism group ,the normal thyroid function group ,subclinical hypothyroidism group and the clinical hypothyroidism group ,which were seperately (15 .543 ± 4 .319) kPa ,(20.083 ± 5 .444) kPa ,(26 .682 ± 5 .676) kPa ,(29 .210 ± 8 .848) kPa .There were significant differences be‐tween groups .( F=14 .925 ,P <0 .01) .The elastic modulus in hyperthyroidism group was lower than the normal thy‐roid function group ,the subclinical hypothyroidism group and the clinical hypothyroidism group .The differences were sta‐tistically significant ( P <0 .05) .The elastic modulus in the normal thyroid function group was lower than the subclinical hypothyroidism group and the clinical hypothyroidism group .The differences were statistically significant ( P < 0 .05) . Conclusion The shear wave elastography Young's modulus have some relevance ,with the clinical manifestations in differ‐ent periods of Hashimoto's thyroiditis ,which can provide a reference for the treatment of HT .