CAJ | 학술논문

目的：观察与研究维生素D、T淋巴细胞亚群与小儿腹泻相关性，以期探寻一种更加合理、有效的方法降低小儿腹泻发生。方法：随机选取70例小儿腹泻者作为研究组，另外再随机抽取健康体检者70例进行对比研究，作为对照组；同时对两组研究对象维生素D、T 淋巴细胞亚群（CD3＋、CD4＋、CD8＋、CD4＋／CD8＋）水平及其相关性和治疗效果等内容进行观察和数据的记录、整理、统计分析。结果：研究组维生素D水平低于对照组且两组T淋巴细胞亚群水平也存在差异，P＜0．05；并且Logistic回归分析显示维生素D、T 淋巴细胞亚群（CD3＋、CD4＋、CD8＋、CD4＋／CD8＋）是腹泻的危险因素，P＜0．05；维生素D水平与T淋巴细胞亚群水平呈正相关性，P＜0．05；同时腹泻患儿治疗措施总有效达95．60％，对其随访半年后，结果显示腹泻再发2例、复发率仅4．4％。结论：维生素D、T淋巴细胞亚群与小儿腹泻具有相关性，而加强维生素D水平的监测、及时、适量补充、纠正维生素D的缺乏或不足为小儿腹泻的预防和治疗提供了新思路、开辟了新途径，值得临床进一步加以研究与推广。
목적：관찰여연구유생소D、T림파세포아군여소인복사상관성，이기탐심일충경가합리、유효적방법강저소인복사발생。방법：수궤선취70례소인복사자작위연구조，령외재수궤추취건강체검자70례진행대비연구，작위대조조；동시대량조연구대상유생소D、T 림파세포아군（CD3＋、CD4＋、CD8＋、CD4＋／CD8＋）수평급기상관성화치료효과등내용진행관찰화수거적기록、정리、통계분석。결과：연구조유생소D수평저우대조조차량조T림파세포아군수평야존재차이，P＜0．05；병차Logistic회귀분석현시유생소D、T 림파세포아군（CD3＋、CD4＋、CD8＋、CD4＋／CD8＋）시복사적위험인소，P＜0．05；유생소D수평여T림파세포아군수평정정상관성，P＜0．05；동시복사환인치료조시총유효체95．60％，대기수방반년후，결과현시복사재발2례、복발솔부4．4％。결론：유생소D、T림파세포아군여소인복사구유상관성，이가강유생소D수평적감측、급시、괄량보충、규정유생소D적결핍혹불족위소인복사적예방화치료제공료신사로、개벽료신도경，치득림상진일보가이연구여추엄。
Objective :Observation and study of vitamin D ,T lymphocyte subsets correlated with diarrhea in children in order to explore a more reasonable and effective way to reduce the occurrence of diarrhea in children .Methods :Random‐ly selected 70 cases of children with diarrhea as a research group ,an additional randomly selected healthy 70 cases were compared ,as a control group ;while the two groups studied vitamin D ,T lymphocyte subsets (CD3 + ,CD4 + ,CD8 + , CD4 + /CD8 + ) level and its relevance and treatment effect was observed and recorded content such as data ,sorting ,sta‐tistical analysis .Results :Study group vitamin D levels lower than the control group and two groups of T lymphocyte subsets are also differences ,P<0 .05 ;and Logistic regression analysis showed that vitamin D ,T lymphocyte subsets (CD3 + ,CD4 + ,CD8 + ,CD4 + /CD8 + )are risk factors for diarrhea ,P<0 .05 ;vitamin D levels and T lymphocyte subsets levels were positively correlated ,P<0 .05 ;while the total effective treatment of diarrhea in children up to 95 .60% ,up six months after its results showed that diarrhea again send two cases ,the recurrence rate was only 4 .4% .Conclusion:Vitamin D ,T lymphocyte subsets correlated with diarrhea in children ,and to strengthen the monitoring of vitamin D levels ,timely and appropriate to add ,correct the lack or inadequacy of infantile diarrhea prevention and treatment of vi‐tamin D provides new ideas and open up a new way ,is worthy of further research and extension .