河北医药
河北醫藥
하북의약
HEBEI MEDICAL JOURNAL
2014年
24期
3701-3704
,共4页
慢性心力衰竭%心功能%肾功能%心肾综合征
慢性心力衰竭%心功能%腎功能%心腎綜閤徵
만성심력쇠갈%심공능%신공능%심신종합정
chronic heart failure%cardiac function%renal function%cardiorenal syndrome
目的：了解慢性心力衰竭患者肾功能异常的发生情况，探讨心肾功能的相互关系。方法选择308例慢性心衰患者（心衰组）和125例心功能正常者（对照组）进行回顾性分析，根据肾小球滤过率（ GFR ）是否＜90 ml? min－1?1,．73 m－2将心衰组分为单纯心衰组（ n =219）和心肾综合征组（ n =89）。对3组研究对象一般资料、基础疾病、化验指标、超声心动图等进行比较分析。结果心衰组患者发生肾功能异常的比率高于对照组，差异有统计学意义（ P ＜0．05）。心肾综合征组肾功能不全分期多为肾功能代偿期和失代偿期。 NYHAⅣ级组伴发肾功能不全的比例明显高于NYHAⅡ、Ⅲ级组，差异有统计学意义（ P ＜0．05），而Ⅱ、Ⅲ级组之间差异无统计学意义（ P ＞0．05）。结论慢性心衰患者常合并不同程度的肾功能异常。心肾综合征患者心功能较单纯慢性心衰患者明显减低。随着心功能的减退，肾功能异常发生率明显上升。
目的：瞭解慢性心力衰竭患者腎功能異常的髮生情況，探討心腎功能的相互關繫。方法選擇308例慢性心衰患者（心衰組）和125例心功能正常者（對照組）進行迴顧性分析，根據腎小毬濾過率（ GFR ）是否＜90 ml? min－1?1,．73 m－2將心衰組分為單純心衰組（ n =219）和心腎綜閤徵組（ n =89）。對3組研究對象一般資料、基礎疾病、化驗指標、超聲心動圖等進行比較分析。結果心衰組患者髮生腎功能異常的比率高于對照組，差異有統計學意義（ P ＜0．05）。心腎綜閤徵組腎功能不全分期多為腎功能代償期和失代償期。 NYHAⅣ級組伴髮腎功能不全的比例明顯高于NYHAⅡ、Ⅲ級組，差異有統計學意義（ P ＜0．05），而Ⅱ、Ⅲ級組之間差異無統計學意義（ P ＞0．05）。結論慢性心衰患者常閤併不同程度的腎功能異常。心腎綜閤徵患者心功能較單純慢性心衰患者明顯減低。隨著心功能的減退，腎功能異常髮生率明顯上升。
목적：료해만성심력쇠갈환자신공능이상적발생정황，탐토심신공능적상호관계。방법선택308례만성심쇠환자（심쇠조）화125례심공능정상자（대조조）진행회고성분석，근거신소구려과솔（ GFR ）시부＜90 ml? min－1?1,．73 m－2장심쇠조분위단순심쇠조（ n =219）화심신종합정조（ n =89）。대3조연구대상일반자료、기출질병、화험지표、초성심동도등진행비교분석。결과심쇠조환자발생신공능이상적비솔고우대조조，차이유통계학의의（ P ＜0．05）。심신종합정조신공능불전분기다위신공능대상기화실대상기。 NYHAⅣ급조반발신공능불전적비례명현고우NYHAⅡ、Ⅲ급조，차이유통계학의의（ P ＜0．05），이Ⅱ、Ⅲ급조지간차이무통계학의의（ P ＞0．05）。결론만성심쇠환자상합병불동정도적신공능이상。심신종합정환자심공능교단순만성심쇠환자명현감저。수착심공능적감퇴，신공능이상발생솔명현상승。
Objective To understand the incidence of abnormal renal function in patients with chronic heart failure ( CHF) ,and to explore the correlation between cardiac function and renal function .Methods The data of 308 patients with chronic heart failure ( CHF group ) and 125 healthy subjects ( control group ) were retrospectively analyzed .According to the glomerular filtration rate,whether (eGFR) <90 ml? min-1? 1.73m-2 or not,the CHF group was subdivided into simple CHF group ( n =219) and cardiorenal syndrome group ( n =89).The general data,basic diseases,test indexes,ultrasound cardiograms were analyzed and compared among the three groups .Results The incidence of abnormal renal function in CHF group was significantly higher than that in control group ( P <0.05).Most of renal inadequacy staging was at renal function compensatory stage or decompensation stage in cardiorenal syndrome group .The incidence of renal inadequacy in patients with NYHA class Ⅳwas significantly higher than those patients with NYHA classⅡand Ⅲ ( P <0.05),however,there was no significant difference between class Ⅱ and class Ⅲ ( P >0.05).Conclusion The patients with chronic heart failure are often complicated by abnormal renal function at different degrees .The cardiac function in patients with cardiorenal syndrome is obviously decreased ,as compared with that in patients with simple chronic heart failure .With the decline of cardiac function , the incidence of abnormal renal function is increased significantly .
