中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
33期
139-140
,共2页
肺部感染%重症监护病房%病原菌%耐药性%分布
肺部感染%重癥鑑護病房%病原菌%耐藥性%分佈
폐부감염%중증감호병방%병원균%내약성%분포
Pulmonary infection%Intensive care unit(ICU)%Pathogen%Drug resistance%Distribution
目的：探究重症病房肺部感染患者的病原菌分布特点及其耐药性。方法：选择210例呼吸重症病房肺部感染患者作为研究对象，分析患者痰液标本、呼吸道分泌物、支气管灌洗液中的病原菌，并统计其分布特点，对主要病原菌进行相应的药敏试验。结果：本组研究共分离122株病原菌，其中肺炎克雷伯菌30株（24.59%），大肠埃希菌16株（13.11%），均明显高于其他病原菌，且与其他病原菌之间的差异显著且具有统计学意义（P﹤0.05）；大肠埃希菌与肺炎克雷伯菌对磺胺甲噁唑／甲氧苄啶的耐药性最高，其耐药率分别为87.50%、76.67%，明显高于对其他抗菌药物的耐药率，且其差异具有统计学意义（P﹤0.05）。结论：本研究中呼吸重症病房肺部感染以大肠埃希菌、肺炎克雷伯菌为主，且这两种病原菌对磺胺甲噁唑／甲氧苄啶耐药性最高，临床治疗时应密切观察病原菌培养及病原菌的耐药性，并依据药敏结果选择适宜的药物，以提高提高抗感染治疗的成功率，并促进患者尽早康复。
目的：探究重癥病房肺部感染患者的病原菌分佈特點及其耐藥性。方法：選擇210例呼吸重癥病房肺部感染患者作為研究對象，分析患者痰液標本、呼吸道分泌物、支氣管灌洗液中的病原菌，併統計其分佈特點，對主要病原菌進行相應的藥敏試驗。結果：本組研究共分離122株病原菌，其中肺炎剋雷伯菌30株（24.59%），大腸埃希菌16株（13.11%），均明顯高于其他病原菌，且與其他病原菌之間的差異顯著且具有統計學意義（P﹤0.05）；大腸埃希菌與肺炎剋雷伯菌對磺胺甲噁唑／甲氧芐啶的耐藥性最高，其耐藥率分彆為87.50%、76.67%，明顯高于對其他抗菌藥物的耐藥率，且其差異具有統計學意義（P﹤0.05）。結論：本研究中呼吸重癥病房肺部感染以大腸埃希菌、肺炎剋雷伯菌為主，且這兩種病原菌對磺胺甲噁唑／甲氧芐啶耐藥性最高，臨床治療時應密切觀察病原菌培養及病原菌的耐藥性，併依據藥敏結果選擇適宜的藥物，以提高提高抗感染治療的成功率，併促進患者儘早康複。
목적：탐구중증병방폐부감염환자적병원균분포특점급기내약성。방법：선택210례호흡중증병방폐부감염환자작위연구대상，분석환자담액표본、호흡도분비물、지기관관세액중적병원균，병통계기분포특점，대주요병원균진행상응적약민시험。결과：본조연구공분리122주병원균，기중폐염극뢰백균30주（24.59%），대장애희균16주（13.11%），균명현고우기타병원균，차여기타병원균지간적차이현저차구유통계학의의（P﹤0.05）；대장애희균여폐염극뢰백균대광알갑오서／갑양변정적내약성최고，기내약솔분별위87.50%、76.67%，명현고우대기타항균약물적내약솔，차기차이구유통계학의의（P﹤0.05）。결론：본연구중호흡중증병방폐부감염이대장애희균、폐염극뢰백균위주，차저량충병원균대광알갑오서／갑양변정내약성최고，림상치료시응밀절관찰병원균배양급병원균적내약성，병의거약민결과선택괄의적약물，이제고제고항감염치료적성공솔，병촉진환자진조강복。
Objective: To explore the ICU patients with lung infection pathogen distribution and drug resistance. Methods: 210 cases of pulmonary infection in respiratory ICU patients as the research objects, analysis of pathogenic bacteria in sputum samples from patients with respiratory secretions, in bronchial lavage fluid, and its distribution characteristics, statistical, drug sensitive tests were made on the main pathogenic bacteria. Results: in this group, 122 strains of pathogenic bacteria were isolated, including 30 strains of Klebsiella pneumoniae (24.59%), Escherichia coli 16 strains (13.11%) were significantly higher than those of other pathogenic bacteria, and the differences with other pathogens significantly and have statistical significance (P<0.05); drug resistance of Escherichia coli and Klebsiella pneumoniae to sulfamethoxazole / trimethoprim is the highest, and the resistant rate were 87.50%, 76.67%, significantly higher than that of other antimicrobial resistance rate, and the difference was statistically significant (P<0.05). Conclusion: Respiratory ICU pulmonary infection with Escherichia coli, Klebsiella pneumonia mainly in this research, and these two kinds of pathogenic bacteria to sulfamethoxazole / trimethoprim resistance is highest, the treatment should closely observe the bacteria culture and drug resistance of pathogenic bacteria, and according to the results of drug susceptibility for appropriate choice of drugs, in order to improve the to improve the anti infection treatment success rate, and promote the patient recover early.
