CAJ | 학술논문

目的：观察自拟活血通络方联合甲钴胺治疗2型糖尿病周围神经病变神经传导速度的疗效。方法：选择符合诊断标准的98例患者，随机分为 A、B、C 三组，A 组(活血通络方+甲钴胺组)，B 组(活血通络方组)，C 组(甲钴胺组），三组均采用4周为1个疗程，共2个疗程，观察治疗前后三组临床症状、肌电图神经传导速度、臂踝指数、血糖、血脂的变化情况。结果：A组总有效率优于 B、C 组（P＜0.05）；A 组肌电图神经传导速度改善优于 B、C 组（P＜0.05），A 组臂踝指数上升优于 B、C 组（P＜0.05），差异具有显著性，治疗后三组血糖、血脂、糖化血红蛋白变化比较无明显差异（P＞0.05）。结论：中西医结合治疗糖尿病周围神经病变有较好疗效，活血通络方在其治疗中的作用值得肯定，且无不良反应。
목적：관찰자의활혈통락방연합갑고알치료2형당뇨병주위신경병변신경전도속도적료효。방법：선택부합진단표준적98례환자，수궤분위 A、B、C 삼조，A 조(활혈통락방+갑고알조)，B 조(활혈통락방조)，C 조(갑고알조），삼조균채용4주위1개료정，공2개료정，관찰치료전후삼조림상증상、기전도신경전도속도、비과지수、혈당、혈지적변화정황。결과：A조총유효솔우우 B、C 조（P＜0.05）；A 조기전도신경전도속도개선우우 B、C 조（P＜0.05），A 조비과지수상승우우 B、C 조（P＜0.05），차이구유현저성，치료후삼조혈당、혈지、당화혈홍단백변화비교무명현차이（P＞0.05）。결론：중서의결합치료당뇨병주위신경병변유교호료효，활혈통락방재기치료중적작용치득긍정，차무불량반응。
Objective: To observe the clinical curative effect of Huoxue Tongluo prescription combined with Methylcobalamin in treatment of lesions of nerve conduction velocity in type 2 diabetic peripheral nerve. Methods: 98 qualified patients were randomly divided into A, B, C three groups,group A (Huoxue Tongluo Decoction + Methycobal group), group B (Huoxue Tongluo Decoction group), C group (Methycobal group),3 groups were treated for 4 weeks as 1 course,a total of 2 courses. The changes of the clinical symptoms, electromyography nerve conduction velocity,ankle brachial index, blood glucose, blood lipids of the three groups were observed before and after treatment. Results: The total effective rate of group A was better than that of B,C group (P< 0.05); group A electromyography nerve conduction velocity is better than B,C group ( P < 0.05),the ankle brachial index of group A was better than that of B, C group (P< 0.05),the difference was significant. After treatment,the blood glucose, blood lipid, glycosylated hemoglobin changes of the three groups had no significant difference (P > 0.05). Conclusion: Traditional Chinese Medicine combined with Western medicine has better curative effect on diabetic peripheral neuropathy. The effect of Huoxue Tongluo Decoction is excellent with no adverse reaction.