河北中医
河北中醫
하북중의
HEBEI JORNAL OF TRADITIONAL CHINESE MEDICINE
2015年
1期
98-100
,共3页
王国强%武美玲%卢海燕%庞艳雷%王雪%田秋君%徐卫国
王國彊%武美玲%盧海燕%龐豔雷%王雪%田鞦君%徐衛國
왕국강%무미령%로해연%방염뢰%왕설%전추군%서위국
一氧化碳中毒%并发症%脑疾病%丹参%红花%注射剂%甲基丙烯酸盐%高压氧
一氧化碳中毒%併髮癥%腦疾病%丹參%紅花%註射劑%甲基丙烯痠鹽%高壓氧
일양화탄중독%병발증%뇌질병%단삼%홍화%주사제%갑기병희산염%고압양
Carbon monoxide poisoning%Complications%Brain disease%Salvia miltiorrhiza%Red flowers%Injection%Methyl acrylate%Hyperbaric oxygen
目的:观察丹红注射液、奥扎格雷钠联合高压氧预防一氧化碳中毒( ACOP )后迟发性脑病(DEACMP)临床疗效。方法将122例重度ACOP患者随机分为2组。治疗组61例给予丹红注射液、奥扎格雷钠联合高压氧治疗,对照组61例施以高压氧治疗。2组均治疗30 d后统计临床疗效,并观察2组治疗前后Barthel指数评分、简易智能精神量表( MMSE)评分、智力残疾评分( AAMD)及发生DEACMP的发生率。结果治疗组临床疗效优于对照组(P<0.05);治疗组DEACMP发生率低于对照组(P<0.05);2组治疗后Bar-thel指数评分、MMSE评分及AAMD评分均升高(P<0.05),且治疗组升高优于对照组(P<0.05)。结论丹红注射液、奥扎格雷钠联合高压氧治疗可有效预防DEACMP的发生,且能提高临床疗效,改善生活质量。
目的:觀察丹紅註射液、奧扎格雷鈉聯閤高壓氧預防一氧化碳中毒( ACOP )後遲髮性腦病(DEACMP)臨床療效。方法將122例重度ACOP患者隨機分為2組。治療組61例給予丹紅註射液、奧扎格雷鈉聯閤高壓氧治療,對照組61例施以高壓氧治療。2組均治療30 d後統計臨床療效,併觀察2組治療前後Barthel指數評分、簡易智能精神量錶( MMSE)評分、智力殘疾評分( AAMD)及髮生DEACMP的髮生率。結果治療組臨床療效優于對照組(P<0.05);治療組DEACMP髮生率低于對照組(P<0.05);2組治療後Bar-thel指數評分、MMSE評分及AAMD評分均升高(P<0.05),且治療組升高優于對照組(P<0.05)。結論丹紅註射液、奧扎格雷鈉聯閤高壓氧治療可有效預防DEACMP的髮生,且能提高臨床療效,改善生活質量。
목적:관찰단홍주사액、오찰격뢰납연합고압양예방일양화탄중독( ACOP )후지발성뇌병(DEACMP)림상료효。방법장122례중도ACOP환자수궤분위2조。치료조61례급여단홍주사액、오찰격뢰납연합고압양치료,대조조61례시이고압양치료。2조균치료30 d후통계림상료효,병관찰2조치료전후Barthel지수평분、간역지능정신량표( MMSE)평분、지력잔질평분( AAMD)급발생DEACMP적발생솔。결과치료조림상료효우우대조조(P<0.05);치료조DEACMP발생솔저우대조조(P<0.05);2조치료후Bar-thel지수평분、MMSE평분급AAMD평분균승고(P<0.05),차치료조승고우우대조조(P<0.05)。결론단홍주사액、오찰격뢰납연합고압양치료가유효예방DEACMP적발생,차능제고림상료효,개선생활질량。
Objective To investigate the clinical effect of Danhong injection and sodium ozagrel combined with hyperbaric oxygen therapy on the prevention of the acute carbon monoxide (CO) poisoning (ACOP) delayed en-cephalopathy (DEACMP).Methods 122 patients with severe ACOP were randomly divided into observation group and control group 61 cases to 61 cases.The observation group was given Danhong injection and sodium ozagrel com -bined with hyperbaric oxygen therapy ,and the control group only with hyperbaric oxygen treatment ,and two groups are of consistent general situation and the foundation treatment .The Barthel index score ,MMSE score,AAMD score and incidence of DEACMP before and after treatment were observed .Results The clinical curative effect of treatment group is better than that of control group (P<0.05).Incidence of DEACMP in treatment group is lower than that in the control group (P<0.05).The Barthel index score,MMSE score and AAMD score after treatment were higher in two groups (P<0.05),and higher in treatment group is better than that of control group (P<0.05).Conclusion Danhong injection and sodium ozagrel combined with hyperbaric oxygen therapy can effectively prevent the occurrence of DEACMP.