CAJ | 학술논문

目的：优选金枣远志胶囊中贯叶金丝桃、黄连、五味子、酸枣仁共同提取的工艺。方法以金丝桃苷提取率为考察指标,采用高效液相色谱法进行测定。采用正交试验与比较试验相结合的方法,对提取工艺中的乙醇浓度、浸泡时间、回流提取时间等因素进行优选。结果乙醇浓度及提取次数对考察指标有显著影响。确定金枣远志胶囊的最佳提取工艺为：加8倍量70%乙醇,浸泡2 h,回流提取1.5 h,过滤,残渣再加6倍量70%乙醇回流提取1.5 h,过滤,合并提取液。结论优选的提取工艺合理可行。
목적：우선금조원지효낭중관협금사도、황련、오미자、산조인공동제취적공예。방법이금사도감제취솔위고찰지표,채용고효액상색보법진행측정。채용정교시험여비교시험상결합적방법,대제취공예중적을순농도、침포시간、회류제취시간등인소진행우선。결과을순농도급제취차수대고찰지표유현저영향。학정금조원지효낭적최가제취공예위：가8배량70%을순,침포2 h,회류제취1.5 h,과려,잔사재가6배량70%을순회류제취1.5 h,과려,합병제취액。결론우선적제취공예합리가행。
Objective To optimize the extraction conditions of Hyperici Perforate Herba, Coptidis Rhizoma, Schisandrae Chinensis Fructus, and Ziziphi Spinosae Semen forJinzao Yuanzhi Capsule.Methods Hyperin extraction rate was set as index, and HPLC was used for determination. The extraction conditions of ethanol concentration, ethanol quantity, extraction time and other factors were studied with orthogonal test and comparative test.Results Ethanol concentration and extracting times were remarkable factors in the test. The optimum extraction technology forJinzao Yuanzhi Capsule was to reflux and extract the materials with 8 times of 70% ethanol for 2 times, reflux extraction for 1.5 hours, filtration. Then 6 times of 70% ethanol was added for 1.5 hours’ reflux, filtering, and merging extracted liquid.Conclusion The optimum extraction technology is reasonable and feasible.