CAJ | 학술논문

目的：观察补肾固精方治疗早期糖尿病肾病的临床疗效。方法将60例阴阳两虚型早期糖尿病肾病患者随机分为治疗组和对照组，治疗组予补肾固精方口服结合西医常规治疗，对照组予西医常规治疗，疗程3个月。比较2组患者治疗前后临床疗效、中医症状积分、尿白蛋白排泄率(UAER)。结果治疗组治疗后中医证候积分低于对照组，差异有统计学意义(P＜0.05)。临床疗效总有效率治疗组为81.48%(22/27)，对照组为64.00%(16/25)，治疗组优于对照组(P＜0.05)。2组 UAER 比较，差异有统计学意义(P＜0.05)。结论在西医常规治疗基础上加服补肾固精方能改善患者临床症状，减轻肾脏损害程度，对早期糖尿病肾病有较好疗效。
목적：관찰보신고정방치료조기당뇨병신병적림상료효。방법장60례음양량허형조기당뇨병신병환자수궤분위치료조화대조조，치료조여보신고정방구복결합서의상규치료，대조조여서의상규치료，료정3개월。비교2조환자치료전후림상료효、중의증상적분、뇨백단백배설솔(UAER)。결과치료조치료후중의증후적분저우대조조，차이유통계학의의(P＜0.05)。림상료효총유효솔치료조위81.48%(22/27)，대조조위64.00%(16/25)，치료조우우대조조(P＜0.05)。2조 UAER 비교，차이유통계학의의(P＜0.05)。결론재서의상규치료기출상가복보신고정방능개선환자림상증상，감경신장손해정도，대조기당뇨병신병유교호료효。
Objective To investigate the effects ofBushen Gujing Recipe in treating early diabetic nephropathy (DN).Methods Sixty patients of early DN with Yin-Yang deficiency syndrome were randomly divided into treatment group and control group, 30 cases in each group. The control group was treated with conventional western medicine treatment, and the treatment group was treated withBushen Gujing Recipe combined with the conventional therapy. The treatment course was three months. The clinical efficacy, integral of TCM syndrome, and urinary albumin excretion rate (UAER) of the two groups were compared.Results After the treatment, the integral of TCM symdrome of the treatment group was lower than control group, showed a statistically significant difference (P<0.05). The total effective rates of clinical efficacy were 81.48% (22/27) in treatment group, and 64.00% (16/25) in control group. The therapeutic effect of treatment group was better than control group (P<0.05). UAER showed a statistically significant difference between two groups (P<0.05).Conclusion Based on the western medicine treatment,Bushen Gujing Recipe can improve the symptoms of patients, alleviate the injury of kidney, and has good efficacy on DN.