中国伤残医学
中國傷殘醫學
중국상잔의학
CHINESE JOURNAL OF TRAUMA AND DISABILITY MEDICINE
2015年
2期
26-28
,共3页
脐带间充质干细胞%移植%急性脑梗死
臍帶間充質榦細胞%移植%急性腦梗死
제대간충질간세포%이식%급성뇌경사
Umbilical cord mesenchymal stem cells%Transplantation%Acute cerebral infarction
目的：：观察脐带间充质干细胞对急性脑梗死患者的神经功能恢复。方法：选择2012年1月~2013年12月我院收治的脑卒中患者16例为治疗组，选取16例脑梗死患者为对照组，所有患者均常规给予抗血小板，强化降脂，营养神经及康复训练等治疗。治疗组在梗塞后第3天行脐带间充质干细胞动脉介入移植治疗。3个月后行功能独立性评分( FIM)。结果：对照组治疗前后FIM评分有统计学差异，(P<0.05)，提示对照组治疗有效。治疗组治疗前后FIM评分有显著统计差异(P<0.01)，提示治疗组治疗效果明显。但治疗组治疗后FIM评分与对照组治疗后FIM评分有统计学差异(P<0.05)，提示治疗组治疗效果优于对照组。结论：脐带间充质干细胞早期一次性移植治疗急性脑梗死有明显临床效果，能够显著促进患者神经功能恢复。
目的：：觀察臍帶間充質榦細胞對急性腦梗死患者的神經功能恢複。方法：選擇2012年1月~2013年12月我院收治的腦卒中患者16例為治療組，選取16例腦梗死患者為對照組，所有患者均常規給予抗血小闆，彊化降脂，營養神經及康複訓練等治療。治療組在梗塞後第3天行臍帶間充質榦細胞動脈介入移植治療。3箇月後行功能獨立性評分( FIM)。結果：對照組治療前後FIM評分有統計學差異，(P<0.05)，提示對照組治療有效。治療組治療前後FIM評分有顯著統計差異(P<0.01)，提示治療組治療效果明顯。但治療組治療後FIM評分與對照組治療後FIM評分有統計學差異(P<0.05)，提示治療組治療效果優于對照組。結論：臍帶間充質榦細胞早期一次性移植治療急性腦梗死有明顯臨床效果，能夠顯著促進患者神經功能恢複。
목적：：관찰제대간충질간세포대급성뇌경사환자적신경공능회복。방법：선택2012년1월~2013년12월아원수치적뇌졸중환자16례위치료조，선취16례뇌경사환자위대조조，소유환자균상규급여항혈소판，강화강지，영양신경급강복훈련등치료。치료조재경새후제3천행제대간충질간세포동맥개입이식치료。3개월후행공능독립성평분( FIM)。결과：대조조치료전후FIM평분유통계학차이，(P<0.05)，제시대조조치료유효。치료조치료전후FIM평분유현저통계차이(P<0.01)，제시치료조치료효과명현。단치료조치료후FIM평분여대조조치료후FIM평분유통계학차이(P<0.05)，제시치료조치료효과우우대조조。결론：제대간충질간세포조기일차성이식치료급성뇌경사유명현림상효과，능구현저촉진환자신경공능회복。
Objective:To observe umbilical cord mesenchymal stem cells on neurological recovery in patients with acute cerebral in-farction. Methods:Select the 16 stroke patients admitted to our hospital for the treatment group in 2012-01/2013-12, 16 cases of cere-bral infarction selected as the control group ,All patients were routinely given anti-platelet , intensive lipid-lowering,nutrition nerve and rehabilitation therapy. Infarction after the third day, the treatment group was transplanted umbilical cord mesenchymal stem cells By artery intervention. Three month after functional independence score ( FIM) . Results:FIM score in the control group before and after treat-ment were significantly different , (P <0. 05), prompt treatment is effective in the control group . FIM score in the Treatment group be-fore and after treatment were significantly statistical difference (P <0. 01),prompt treatment was also effective in the Treatment group . But after treatment, the treatment and control groups FIM scores were statistically significant , (P <0. 05), prompt treatment group was better than the control group. Conclusion:Umbilical cord mesenchymal stem cells in the treatment of acute cerebral infarction might be sig-nificant clinical effect by early single transplanted,which could significantly promote the recovery of neurological function in patients.
