CAJ | 학술논문

壳聚糖因其具有良好的生物学特性而成为药物载体研究的热点。药物经壳聚糖负载后，不仅能够达到缓释控释的目的，还能够改变药物的给药方式，降低药物不良反应，提高药物生物利用度。本文就壳聚糖微球的制备及其在药物载体中的应用作一综述。
각취당인기구유량호적생물학특성이성위약물재체연구적열점。약물경각취당부재후，불부능구체도완석공석적목적，환능구개변약물적급약방식，강저약물불량반응，제고약물생물이용도。본문취각취당미구적제비급기재약물재체중적응용작일종술。
Chitosan has been intensively studied as a novel drug carrier because of its excellent biological charac-teristics.Loaded in the chitosan,the drug can be released not only sustainably but also in controlled modes,re-sulting in reduced adverse drug reactions and enhanced bioavailability.This review paper is focused on the prep-aration and applications of chitosan microspheres as drug carrier materials.