南昌大学学报(医学版)
南昌大學學報(醫學版)
남창대학학보(의학판)
ACTA ACADEMIAE MEDICINAE JIANGXI
2014年
11期
72-74,93
,共4页
射频消融%脾脏良性肿瘤%脾部分切除%免疫功能
射頻消融%脾髒良性腫瘤%脾部分切除%免疫功能
사빈소융%비장량성종류%비부분절제%면역공능
radiofrequency ablation%benign splenic tumors%partial splenectomy%immune function
目的:探讨射频辅助脾部分切除术治疗脾脏良性肿瘤的疗效及对免疫功能的影响。方法将40例行手术治疗的脾脏良性肿瘤患者根据手术方式的不同,分为射频组(22例,射频辅助脾部分切除术)和对照组(18例,常规脾部分切除术)。对2组患者的手术相关指标(手术时间、手术出血量、住院时间、住院费用、术后并发症),术前、术后4周外周血免疫球蛋白(IgG、IgA、IgM)及 T 淋巴细胞亚群(CD4+、CD8+、CD4+/CD8+)的情况进行比较。结果2组患者的手术时间、住院费用及术后并发症发生例数比较差异均无统计学意义(均 P >0.05)。射频组的手术出血量及住院时间显著少于对照组(均 P <0.05),术后无并发症发生;对照组有 2例患者因术后大出血再次手术治疗。射频组患者术后4周免疫球蛋白及 T 淋巴细胞亚群与术前及对照组比较差异均无统计学意义(均 P >0.05)。结论射频辅助脾部分切除术可有效地治疗脾脏良性肿瘤,出血量少、住院时间短,且不损害患者免疫功能。
目的:探討射頻輔助脾部分切除術治療脾髒良性腫瘤的療效及對免疫功能的影響。方法將40例行手術治療的脾髒良性腫瘤患者根據手術方式的不同,分為射頻組(22例,射頻輔助脾部分切除術)和對照組(18例,常規脾部分切除術)。對2組患者的手術相關指標(手術時間、手術齣血量、住院時間、住院費用、術後併髮癥),術前、術後4週外週血免疫毬蛋白(IgG、IgA、IgM)及 T 淋巴細胞亞群(CD4+、CD8+、CD4+/CD8+)的情況進行比較。結果2組患者的手術時間、住院費用及術後併髮癥髮生例數比較差異均無統計學意義(均 P >0.05)。射頻組的手術齣血量及住院時間顯著少于對照組(均 P <0.05),術後無併髮癥髮生;對照組有 2例患者因術後大齣血再次手術治療。射頻組患者術後4週免疫毬蛋白及 T 淋巴細胞亞群與術前及對照組比較差異均無統計學意義(均 P >0.05)。結論射頻輔助脾部分切除術可有效地治療脾髒良性腫瘤,齣血量少、住院時間短,且不損害患者免疫功能。
목적:탐토사빈보조비부분절제술치료비장량성종류적료효급대면역공능적영향。방법장40례행수술치료적비장량성종류환자근거수술방식적불동,분위사빈조(22례,사빈보조비부분절제술)화대조조(18례,상규비부분절제술)。대2조환자적수술상관지표(수술시간、수술출혈량、주원시간、주원비용、술후병발증),술전、술후4주외주혈면역구단백(IgG、IgA、IgM)급 T 림파세포아군(CD4+、CD8+、CD4+/CD8+)적정황진행비교。결과2조환자적수술시간、주원비용급술후병발증발생례수비교차이균무통계학의의(균 P >0.05)。사빈조적수술출혈량급주원시간현저소우대조조(균 P <0.05),술후무병발증발생;대조조유 2례환자인술후대출혈재차수술치료。사빈조환자술후4주면역구단백급 T 림파세포아군여술전급대조조비교차이균무통계학의의(균 P >0.05)。결론사빈보조비부분절제술가유효지치료비장량성종류,출혈량소、주원시간단,차불손해환자면역공능。
ABSTRACT:Objective To explore the effects of radiofrequency-assisted partial splenectomy on benign splenic tumors and immune function.Methods Forty patients with benign splenic tumors were assigned to receive either radiofrequency-assisted partial splenectomy(radiofrequency group, n=22)or conventional partial splenectomy(control group,n=18).Surgery-related situation(op-erative time,blood loss,hospital stay,hospitalization cost and postoperative complications)and peripheral blood immunoglobulin(IgG,IgA and IgM)and T-lymphocyte subsets(CD4 + ,CD8 +and CD4+/CD8+ )before and 4 weeks after operation were compared between the two groups. Results There were no significant differences in operative time,hospitalization cost and incidence of postoperative complications between the two groups(P >0.05).Compared with control group, the blood loss and hospital stay significantly decreased in radiofrequency group(P <0.05).In ra-diofrequency group,no postoperative complications occurred and no changes in immunoglobulin and T-lymphocyte subsets were observed 4 weeks after operation.However,2 patients underwent reoperation because of postoperative massive haemorrhage in control group.No significant differ-ences in immunoglobulin and T-lymphocyte subsets were found between the two groups 4 weeks after operation(P >0.05).Conclusion Radiofrequency-assisted partial splenectomy can effective-ly treat benign splenic tumors,reduce blood loss,shorten hospitalization stay,and have no effect on immune function.