CAJ | 학술논문

目的：探讨老年短暂性脑缺血（TIA）与缺血性脑卒中（IS）颈动脉结构与血流动力学的不同，以达到早期识别并防治缺血性脑血管病的目的。方法选择缺血性脑卒中患者40例（IS 组），短暂性脑缺血发作患者48例（TIA组），采用 Siemens ACUSON 512型彩色多普勒超声诊断仪检测2组患者颈动脉结构及血流动力学参数。结果TIA 组颈动脉内膜中层厚度（IMT）及斑块检出率均明显低于 IS 组，差异有统计学意义（P ＜0．05）；TIA 组颈内动脉（ICA）、椎动脉（VA）中血流速度（PSV）、舒张末期血流速度（EDV）、时间平均血流速度（TAV）均明显高于 IS 组，搏动指数（PI）、阻力指数（RI）均明显低于 IS 组，差异有统计学意义（P ＜0．05）。结论TIA 的出现往往预示着 IS的发生，临床中可通过彩色多普勒超声检查颈动脉内膜中层厚度、斑块及血流动力学情况，以实现对缺血性脑血管病的早期诊断和预防。
목적：탐토노년단잠성뇌결혈（TIA）여결혈성뇌졸중（IS）경동맥결구여혈류동역학적불동，이체도조기식별병방치결혈성뇌혈관병적목적。방법선택결혈성뇌졸중환자40례（IS 조），단잠성뇌결혈발작환자48례（TIA조），채용 Siemens ACUSON 512형채색다보륵초성진단의검측2조환자경동맥결구급혈류동역학삼수。결과TIA 조경동맥내막중층후도（IMT）급반괴검출솔균명현저우 IS 조，차이유통계학의의（P ＜0．05）；TIA 조경내동맥（ICA）、추동맥（VA）중혈류속도（PSV）、서장말기혈류속도（EDV）、시간평균혈류속도（TAV）균명현고우 IS 조，박동지수（PI）、조력지수（RI）균명현저우 IS 조，차이유통계학의의（P ＜0．05）。결론TIA 적출현왕왕예시착 IS적발생，림상중가통과채색다보륵초성검사경동맥내막중층후도、반괴급혈류동역학정황，이실현대결혈성뇌혈관병적조기진단화예방。
ABSTRACT:Objective To investigate the differences in carotid artery structure and hemody-namic parameters between elderly patients with transient ischemic attacks(TIA)and elderly pa-tients with ischemic stroke(IS),and to early identify and prevent the ischemic cerebrovascular disease.Methods Carotid artery structure and hemodynamic parameters were measured using ul-trasound system in 40 patients with IS(IS group)and 48 patients with TIA(TIA group).Results Compared with IS group,the carotid artery intima-media thickness(IMT),plaque detection rate, pulsatility index and resistance index in the internal carotid artery(ICA)and vertebral artery (VA)significantly decreased,but the peak systolic velocity,end diastolic velocity and time-aver-aged velocity obviously increased in TIA group(P <0.05).Conclusion The TIA often heralds the occurrence of IS.Doppler ultrasound can be used to measure the IMT,plaques and hemody-namics for the early diagnosis and prevention of ischemic cerebrovascular disease.