CAJ | 학술논문

目的：探讨2型糖尿病患者颈动脉硬化（CAS）及下肢动脉硬化（LLAS）与颅内动脉硬化的关系及其对颅内动脉硬化的预测作用。方法：74例2型糖尿病患者行颈、下肢动脉血管超声及头颅 MRA检查，行Pearson、Binary Logistic 分析。结果：随着周围动脉硬化程度的增高颅内动脉硬化有增加趋势；LLAS 及 CAS＋ LLAS 与颅内动脉硬化的相关系数为0．28（P ＜0．05）和0．33（P ＜0．05），OR 值为0．14（P ＜0．05）和9．28（P ＜0．05），AUC为70．30％（P＜0．05）和70．60％（P＜0．05），界值点均为2级。结论：LLAS及CAS＋LLAS为2型糖尿病合并颅内动脉硬化的独立危险因素，有一定的预测作用。
목적：탐토2형당뇨병환자경동맥경화（CAS）급하지동맥경화（LLAS）여로내동맥경화적관계급기대로내동맥경화적예측작용。방법：74례2형당뇨병환자행경、하지동맥혈관초성급두로 MRA검사，행Pearson、Binary Logistic 분석。결과：수착주위동맥경화정도적증고로내동맥경화유증가추세；LLAS 급 CAS＋ LLAS 여로내동맥경화적상관계수위0．28（P ＜0．05）화0．33（P ＜0．05），OR 치위0．14（P ＜0．05）화9．28（P ＜0．05），AUC위70．30％（P＜0．05）화70．60％（P＜0．05），계치점균위2급。결론：LLAS급CAS＋LLAS위2형당뇨병합병로내동맥경화적독립위험인소，유일정적예측작용。
Objective To investigate the value of carotid and lower limbs arteries atherosclerosis in prediction of intracranial atherosclerosis combined with type 2 diabetes (T2DM). Methods Seventy-four patients with T2DM received the carotid artery , lower limbs arterial color Doppler ultrasound and cranial MRA examination. The data was analysised by Pearson correlation and Binary Logistic methods. Results With the increasement of degree of peri-arterial atherosclerosis , the intracranial arteriosclerosis was in a trend of increase. The correlation coefficients, OR values and AUC of LLAS and CAS + LLAS for intracranial atherosclerosis were 0.28 (P < 0.05) and 0.33 (P < 0.05), 0.14 (P < 0.05) and 9.28 (P < 0.05), 70.30% (P < 0.05) and 70.60% (P < 0.05), respectively. The cut-off point of LLAS and CAS + LLAS was lever 2. Conclusion The LLAS and CAS + LLAS with T2DM are independent risk factors for intracranial atherosclerosis , owning certain forecast values.