CAJ | 학술논문

目的：分析人工髋关节置换术后抗生素使用24 h与72 h对近期感染率的影响。方法：髋关节置换患者共535例，根据抗菌药物使用时间随机分为两组，A组：抗生素使用至术后24 h 停用。 B组：抗生素使用至术后72 h停用，统计两组间术后感染发生率。结果：术后确诊感染者共有22例，其中 A组12例（感染率为4．396％），B组10例（3．817％），两组感染发生率的比较，差异无统计学意义（P＝0．736）。结论：对于髋关节置换患者，延长术后抗生素使用时间（超过48 h ）并未降低近期感染的机会。
목적：분석인공관관절치환술후항생소사용24 h여72 h대근기감염솔적영향。방법：관관절치환환자공535례，근거항균약물사용시간수궤분위량조，A조：항생소사용지술후24 h 정용。 B조：항생소사용지술후72 h정용，통계량조간술후감염발생솔。결과：술후학진감염자공유22례，기중 A조12례（감염솔위4．396％），B조10례（3．817％），량조감염발생솔적비교，차이무통계학의의（P＝0．736）。결론：대우관관절치환환자，연장술후항생소사용시간（초과48 h ）병미강저근기감염적궤회。
Objective To assess the effects of different administration timing of prophylactic antibiotics on infections after hip arthroplasty. Methods 535 patients having undergone arthroplasty were divided into two groups: the experiment group (n=273)and the control group (n=262): The former groupwere administered with antibiotics until 24 hours postoperatively and the latter until 72 hours postoperatively. The two groups were compared in terms of postoperative infection rate. Results The infection rates in the experimental groupand the control group were 4.396%and 3..817%, with insignificant differencebetween them. Conclusion For those patients undergoing hip arthroplasty, extended administration of antibiotics after operation (over 48 hours) may not reduce the risk of recent the infection rate.