CAJ | 학술논문

目的：研究阿司匹林对人结肠癌耐药细胞株Caco－2增殖和凋亡的影响。方法采用四甲基偶氮唑盐（ MTT）法测定阿司匹林对Caco－2增殖抑制的影响，流式细胞术（ FCM）法检测细胞凋亡指数，电镜等技术。结果不同浓度的阿司匹林对人结肠癌耐药细胞株Caco－2有较强的抑制作用，且呈剂量及时间依赖性。结论阿司匹林能够显著抑制人结肠癌耐药细胞株Caco－2增殖及诱导凋亡。
목적：연구아사필림대인결장암내약세포주Caco－2증식화조망적영향。방법채용사갑기우담서염（ MTT）법측정아사필림대Caco－2증식억제적영향，류식세포술（ FCM）법검측세포조망지수，전경등기술。결과불동농도적아사필림대인결장암내약세포주Caco－2유교강적억제작용，차정제량급시간의뢰성。결론아사필림능구현저억제인결장암내약세포주Caco－2증식급유도조망。
Objectives This study aims to investigate the effects of ginsenoside Rg3 on the proliferation and migration of Caco-2 cells.Methods Inhibition of Caco-2 proliferation,apoptosis indexes within human colon cancer cell line Caco-2 cells were respec-tively detected by methyl thiazolyl tetrazolium ( MTT) ,flow cytometry ( FCM) and Electron Microscope Technology.Results Differ-ent concentrations of TP showed significant inhibitory effects on human colon cancer cell line Caco-2.Conclusions TP can promote the apoptosis of human colon cancer cell line Caco-2.