CAJ | 학술논문

慢性阻塞性肺疾病（ COPD）是我国常见病、多发病，发病率越来越高，其急性加重多由感染引起，核心是气道炎症。在炎症反复刺激过程中，不断的启动凝血纤溶系统，凝血功能改变，致血液高凝状态，即血栓前状态（ PTS）。这种血栓前状态极易并发深静脉血栓、肺栓塞及心血管事件等。因此，COPD患者早期及时进行抗凝治疗越来越受到临床医生的重视，而低分子量肝素治疗是临床较为成熟安全有效的抗凝治疗措施。
만성조새성폐질병（ COPD）시아국상견병、다발병，발병솔월래월고，기급성가중다유감염인기，핵심시기도염증。재염증반복자격과정중，불단적계동응혈섬용계통，응혈공능개변，치혈액고응상태，즉혈전전상태（ PTS）。저충혈전전상태겁역병발심정맥혈전、폐전새급심혈관사건등。인차，COPD환자조기급시진행항응치료월래월수도림상의생적중시，이저분자량간소치료시림상교위성숙안전유효적항응치료조시。
Chronic obstructive pulmonary disease( COPD) is a common disease and frequently-occurring disease in our country, Its incidence trends to raise year by year,acute exacerbations of Chronic obstructive pulmonary diseases(AECOPD) is usually caused by infection and pulmonary in flammation is the core.Inflammation of the stimulated repeatedly,start the blood coagulation systerm and fibrinolytic system,blood coagulation function is changed,lead to high blood coagulation state,also is Prethrombotic state(PTS). This state easily complicated by deep vein thrombosis、Pulmonary embolism、Cardiovascular events and so on.Therefore,early antico-agulant therapy more and more get the attention of the clinicians.And low-molecular-weight heparin anticoagulation therapy is safe and effective clinical anticoagulant therapy.