药学与临床研究
藥學與臨床研究
약학여림상연구
PHARMACEUTICAL AND CLINICAL RESEARCH
2014年
6期
562-565
,共4页
腹腔感染%抗菌药%联合用药%病原菌
腹腔感染%抗菌藥%聯閤用藥%病原菌
복강감염%항균약%연합용약%병원균
Abdominal cavity infection%Antimicrobials%Combination%Pathogen
目的：调查分析我院腹腔感染患者的抗菌药使用情况，指导临床合理应用抗菌药物治疗腹腔感染。方法：抽查我院2014年1~7月份腹腔感染出院患者病历共220份，对抗菌药使用情况进行统计分析。结果：220份病历均使用了抗菌药，共涉及10类24种：单一用药92例（占41.8%），二联用药126例（占57.3%），三联用药2例（占0.91%）。应用的抗菌药物以头孢菌素类（含加酶抑制剂复合制剂）的使用率最高；其次为青霉素类（含加酶抑制剂复合制剂）；排在第三位的是硝基咪唑类。以两联用药为主，联用类别主要为β-内酰胺类联合硝基咪唑类及β-内酰胺类联合喹诺酮类。平均用药时间5.57 d。进行细菌培养及药敏试验的病例有47例，检出的致病菌主要是革兰阴性菌，有大肠埃希菌、铜绿假单胞菌及肺炎克雷伯菌。结论：我院腹腔感染患者抗菌药应用基本合理，但也存在联合用药不合理、疗程超长等情况，应进一步加强管理。
目的：調查分析我院腹腔感染患者的抗菌藥使用情況，指導臨床閤理應用抗菌藥物治療腹腔感染。方法：抽查我院2014年1~7月份腹腔感染齣院患者病歷共220份，對抗菌藥使用情況進行統計分析。結果：220份病歷均使用瞭抗菌藥，共涉及10類24種：單一用藥92例（佔41.8%），二聯用藥126例（佔57.3%），三聯用藥2例（佔0.91%）。應用的抗菌藥物以頭孢菌素類（含加酶抑製劑複閤製劑）的使用率最高；其次為青黴素類（含加酶抑製劑複閤製劑）；排在第三位的是硝基咪唑類。以兩聯用藥為主，聯用類彆主要為β-內酰胺類聯閤硝基咪唑類及β-內酰胺類聯閤喹諾酮類。平均用藥時間5.57 d。進行細菌培養及藥敏試驗的病例有47例，檢齣的緻病菌主要是革蘭陰性菌，有大腸埃希菌、銅綠假單胞菌及肺炎剋雷伯菌。結論：我院腹腔感染患者抗菌藥應用基本閤理，但也存在聯閤用藥不閤理、療程超長等情況，應進一步加彊管理。
목적：조사분석아원복강감염환자적항균약사용정황，지도림상합리응용항균약물치료복강감염。방법：추사아원2014년1~7월빈복강감염출원환자병력공220빈，대항균약사용정황진행통계분석。결과：220빈병력균사용료항균약，공섭급10류24충：단일용약92례（점41.8%），이련용약126례（점57.3%），삼련용약2례（점0.91%）。응용적항균약물이두포균소류（함가매억제제복합제제）적사용솔최고；기차위청매소류（함가매억제제복합제제）；배재제삼위적시초기미서류。이량련용약위주，련용유별주요위β-내선알류연합초기미서류급β-내선알류연합규낙동류。평균용약시간5.57 d。진행세균배양급약민시험적병례유47례，검출적치병균주요시혁란음성균，유대장애희균、동록가단포균급폐염극뢰백균。결론：아원복강감염환자항균약응용기본합리，단야존재연합용약불합리、료정초장등정황，응진일보가강관리。
Objective: To analyze the utilization of antibacterial agents in abdominal infection cases, and to provide guidance for rational use of antibacterial agents in the clinic. Methods: A total of 220 abdominal infection cases were collected in our hospital from January to July of 2014, and the data of antimicrobial agents use were statistically analyzed. Results: There were a total of 24 drugs of 10 categories used in 220 cases, with 92 cases using single drug (57.3%), 126 cases using two drugs (57.3%), and only two cases using three drugs (0.91%). The top three varieties of antibacterials included cephalosporins (with enzyme inhibitor compound preparations), penicillins (with enzyme inhibitor compound preparations) and nitroimidazoles. Two drugs combination was the main application in the antimicrobial drugs, the main combination types were β-lactam+quinolones and β-lactam+ nitroimidazoles. The average medication time was 5.57 d. Bacterial cultivation and drug sensitivity test were conducted in 47 cases, among which most of them were Gram negative bacteria infections, such as Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae. Conclusion: The utilization of antibacterial agents in abdominal infection cases in our hospital was essentially rational. However, there were cases of irrational use and long time use of antibacterials, which needs strengthened management.
