CAJ | 학술논문

羟考酮（oxycodone）是由蒂巴因（thebaine）改造合成的阿片类中枢神经镇痛药。近几年，随着新的羟考酮剂型的开发，该药物在急性疼痛以及慢性疼痛的控制中均广泛使用，并且出现与少量阿片类药物拮抗剂联用镇痛的方式。本文综述羟考酮的基本药理学性质以及临床应用进展。
간고동（oxycodone）시유체파인（thebaine）개조합성적아편류중추신경진통약。근궤년，수착신적간고동제형적개발，해약물재급성동통이급만성동통적공제중균엄범사용，병차출현여소량아편류약물길항제련용진통적방식。본문종술간고동적기본약이학성질이급림상응용진전。
Oxycodone is a central nervous system opioid analgesics reformed from thebaine. In recent years, with the development of the formulation of oxycodone, it has been an effective treatment for acute pain and chronic pain. In addition, oxycodone plus opioid receptor antagonist has been developed to improve analgesia in clinical. This article reviews the basic pharmacological properties of oxycodone and its clinical treatment development.