世界科学技术-中医药现代化
世界科學技術-中醫藥現代化
세계과학기술-중의약현대화
WORLD SCIENCE AND TECHNOLOGY-MODERNIZATION OF TRADITIONAL CHINESE MEDICINE
2014年
11期
2430-2434
,共5页
原发性痛经%针灸%活血理气止痛汤%布洛芬%临床疗效
原髮性痛經%針灸%活血理氣止痛湯%佈洛芬%臨床療效
원발성통경%침구%활혈리기지통탕%포락분%림상료효
Primary dysmenorrheal%acupuncture%Huo-Xue Li-Qi Zhi-Tong decoction%ibuprofen%clinical effect
目的：观察活血理气止痛汤联合针灸治疗原发性痛经（PD）气滞血瘀证的疗效。方法：选取2011年1月-2014年1月于重庆市中医研究院治疗的130例PD患者为研究对象，将其随机分为治疗组与对照组，各65例，对照组给予布洛芬缓释胶囊治疗，治疗组给予活血理气止痛汤联合针灸治疗，治疗3个月经周期后，观察两组治疗前后的视觉疼痛模拟评分（VAS评分）、前列腺素F2a（PGF2a）、前列腺素E2（PGE2）、PGF2a/PGE2、临床疗效、复发情况。结果：与治疗前比较，治疗组与对照组均可明显降低VAS评分（P<0.05），明显降低PGF2a，增加PGE2含量，降低PGF2a/PGE2比值（P<0.05）；与对照组比较，治疗组痊愈率、总有效率明显增加（P<0.05），VAS评分在治疗后第3个月经周期明显降低（P<0.05），PGF2a/PGE2比值明显降低（P<0.05）。治疗结束6个月、9个月、12个月后，治疗组的复发率均明显低于对照组（P<0.05）。结论：活血理气止痛汤联合针灸治疗PD，可以调节PD患者血浆PGF2a与PGE2含量，降低复发率，对PD患者具有明显效果，优于西药治疗，值得推广。
目的：觀察活血理氣止痛湯聯閤針灸治療原髮性痛經（PD）氣滯血瘀證的療效。方法：選取2011年1月-2014年1月于重慶市中醫研究院治療的130例PD患者為研究對象，將其隨機分為治療組與對照組，各65例，對照組給予佈洛芬緩釋膠囊治療，治療組給予活血理氣止痛湯聯閤針灸治療，治療3箇月經週期後，觀察兩組治療前後的視覺疼痛模擬評分（VAS評分）、前列腺素F2a（PGF2a）、前列腺素E2（PGE2）、PGF2a/PGE2、臨床療效、複髮情況。結果：與治療前比較，治療組與對照組均可明顯降低VAS評分（P<0.05），明顯降低PGF2a，增加PGE2含量，降低PGF2a/PGE2比值（P<0.05）；與對照組比較，治療組痊愈率、總有效率明顯增加（P<0.05），VAS評分在治療後第3箇月經週期明顯降低（P<0.05），PGF2a/PGE2比值明顯降低（P<0.05）。治療結束6箇月、9箇月、12箇月後，治療組的複髮率均明顯低于對照組（P<0.05）。結論：活血理氣止痛湯聯閤針灸治療PD，可以調節PD患者血漿PGF2a與PGE2含量，降低複髮率，對PD患者具有明顯效果，優于西藥治療，值得推廣。
목적：관찰활혈리기지통탕연합침구치료원발성통경（PD）기체혈어증적료효。방법：선취2011년1월-2014년1월우중경시중의연구원치료적130례PD환자위연구대상，장기수궤분위치료조여대조조，각65례，대조조급여포락분완석효낭치료，치료조급여활혈리기지통탕연합침구치료，치료3개월경주기후，관찰량조치료전후적시각동통모의평분（VAS평분）、전렬선소F2a（PGF2a）、전렬선소E2（PGE2）、PGF2a/PGE2、림상료효、복발정황。결과：여치료전비교，치료조여대조조균가명현강저VAS평분（P<0.05），명현강저PGF2a，증가PGE2함량，강저PGF2a/PGE2비치（P<0.05）；여대조조비교，치료조전유솔、총유효솔명현증가（P<0.05），VAS평분재치료후제3개월경주기명현강저（P<0.05），PGF2a/PGE2비치명현강저（P<0.05）。치료결속6개월、9개월、12개월후，치료조적복발솔균명현저우대조조（P<0.05）。결론：활혈리기지통탕연합침구치료PD，가이조절PD환자혈장PGF2a여PGE2함량，강저복발솔，대PD환자구유명현효과，우우서약치료，치득추엄。
This study was aimed to observe effects of qi-stagnation and blood-stasis pattern of primary dysmenorrhea (PD) treated by Huo-Xue Li-Qi Zhi-Tong (HXLQZT) decoction combined with acupuncture. A total of 130 PD patients, which were selected from January 2011 to January 2014 at the Chongqing Academy of Traditional Chinese Medicine, were randomly divided into the treatment group and the control group, with 65 cases in each group. The control group was treated with ibuprofen sustained release capsules and the treatment group was given HXLQZT decoction combined with acupuncture. After the treatment of 3 menstrual cycles, indexes were observed from aspects including visual analogue score (VAS), PGF2a, PGE2, PGF2a/PGE2, clinical efficacy and relapse circumstance before and after treatment in two groups. The results showed that compared with pretreatment, there were obvious decreased VAS in both the treatment group and the control group (P<0.05), decreased PGF2a, increased PGE2 content, and obvious decreased PGF2a/PGE2 ratio (P < 0.05). Compared with the control group, the cure rate and the total efficiency of the treatment group were significantly increased (P < 0.05). The VAS was significantly decreased in the third menstrual cycle after treatment (P < 0.05). The ratio of PGF2a/PGE2 was significantly decreased (P < 0.05). In the end of 6-month, 9-month and 12-month treatment, relapse rates of the treatment group were significantly lower than those of the control group (P<0.05). It was concluded that HXLQZT decoction combined with acupuncture can regulated the plasma content of PGF2a and PGE2 and reduce the relapse rate among PD patients. It had obvious effect on PD patients with superior treatment effect compared to western medicine treatment. Therefore, it was worthy of a promotion.
