世界科学技术-中医药现代化
世界科學技術-中醫藥現代化
세계과학기술-중의약현대화
WORLD SCIENCE AND TECHNOLOGY-MODERNIZATION OF TRADITIONAL CHINESE MEDICINE
2014年
11期
2415-2419
,共5页
李路广%李欢欢%张盼奎%余学庆%李建生
李路廣%李歡歡%張盼奎%餘學慶%李建生
리로엄%리환환%장반규%여학경%리건생
慢性阻塞性肺疾病%舒肺贴%刺激强度%临床疗效
慢性阻塞性肺疾病%舒肺貼%刺激彊度%臨床療效
만성조새성폐질병%서폐첩%자격강도%림상료효
Chronic obstructive pulmonary disease%Shu-lung post%stimulation intensity%clinical efficacy
目的:分析舒肺贴不同刺激强度对慢性阻塞性肺疾病(COPD)临床疗效的影响,以确定最佳刺激强度。方法:采用多中心、随机、对照的临床试验设计,以COPD稳定期患者为研究对象,随机分为发泡组与未发泡组,在“三伏天”前的第10天、“三伏天”内的第1、10、20天,“三伏天”后的第10天各贴敷1次。结果:共纳入164例,其中脱落18例,符合方案146例。发泡组与未发泡组之间治疗后年急性加重次数比较差异有统计学意义(P<0.05);随访8个月临床症状与体征总分比较差异有统计学意义(P<0.01)。结论:舒肺贴不同刺激强度与临床疗效呈正相关性。
目的:分析舒肺貼不同刺激彊度對慢性阻塞性肺疾病(COPD)臨床療效的影響,以確定最佳刺激彊度。方法:採用多中心、隨機、對照的臨床試驗設計,以COPD穩定期患者為研究對象,隨機分為髮泡組與未髮泡組,在“三伏天”前的第10天、“三伏天”內的第1、10、20天,“三伏天”後的第10天各貼敷1次。結果:共納入164例,其中脫落18例,符閤方案146例。髮泡組與未髮泡組之間治療後年急性加重次數比較差異有統計學意義(P<0.05);隨訪8箇月臨床癥狀與體徵總分比較差異有統計學意義(P<0.01)。結論:舒肺貼不同刺激彊度與臨床療效呈正相關性。
목적:분석서폐첩불동자격강도대만성조새성폐질병(COPD)림상료효적영향,이학정최가자격강도。방법:채용다중심、수궤、대조적림상시험설계,이COPD은정기환자위연구대상,수궤분위발포조여미발포조,재“삼복천”전적제10천、“삼복천”내적제1、10、20천,“삼복천”후적제10천각첩부1차。결과:공납입164례,기중탈락18례,부합방안146례。발포조여미발포조지간치료후년급성가중차수비교차이유통계학의의(P<0.05);수방8개월림상증상여체정총분비교차이유통계학의의(P<0.01)。결론:서폐첩불동자격강도여림상료효정정상관성。
This study was aimed to analyze the therapeutic effect of Shu-lung post with different stimula-tion intensities on chronic obstructive pulmonary disease (COPD), in order to determine the best stimulus intensity. A multicenter, randomized, controlled clinical trial was designed to take COPD patients at stable stage as study sub-jects. Patients were randomly divided into two groups, which were the foaming group and non-foaming group. The application was given 10 days before the summer "dog days", on the 1st, 10th and 20th day within the "dog days", and 10 days after the "dog days". The results showed that a total of 164 cases were enrolled in the study, with 18 drop-out cases, and 146 cases fitted in the program. There was statistical difference on acute exacerbation frequency <br> after treatment between the foaming group and non-foaming group (P < 0.05). There were statistical differences on clinical symptoms and signs of total score (P< 0.01) during the 8-month follow-up. It was concluded that Shu-lung post with different stimulation intensities were positively correlation with clinical efficacy.