CAJ | 학술논문

刺五加是一种常用中药材，主要药用部位为干燥根、根茎或茎，自古便被列为上品，有诸多药用功效。对刺五加相关发明专利进行专题分析，有助于了解其发明专利申请现状及发展趋势，进而推进该药物的产品研发和产业化发展，促进科技成果转化。本文使用《Espacenet》及《世界传统药物数据库》进行专利检索，并利用Python、R语言等工具对检索结果进行收集、筛选、整理、统计和分析，深入剖析刺五加相关发明专利申请的现状与发展趋势，为刺五加的开发提供参考。结果表明，刺五加的发明专利申请热度逐年提高，但是总申请数量相对于其悠久的应用历史而言还不够。刺五加相关发明专利申请主要来自于中、韩、日、俄、美等国家和地区，涉及的主要临床应用依次为全身保护/抗毒剂、治疗神经系统、消化系统、代谢、免疫或过敏性疾病等，多与补虚类中药，特别是补气药联用。
자오가시일충상용중약재，주요약용부위위간조근、근경혹경，자고편피렬위상품，유제다약용공효。대자오가상관발명전리진행전제분석，유조우료해기발명전리신청현상급발전추세，진이추진해약물적산품연발화산업화발전，촉진과기성과전화。본문사용《Espacenet》급《세계전통약물수거고》진행전리검색，병이용Python、R어언등공구대검색결과진행수집、사선、정리、통계화분석，심입부석자오가상관발명전리신청적현상여발전추세，위자오가적개발제공삼고。결과표명，자오가적발명전리신청열도축년제고，단시총신청수량상대우기유구적응용역사이언환불구。자오가상관발명전리신청주요래자우중、한、일、아、미등국가화지구，섭급적주요림상응용의차위전신보호/항독제、치료신경계통、소화계통、대사、면역혹과민성질병등，다여보허류중약，특별시보기약련용。
A . Senticosus is a common medicinal plants, mainly used parts are the dried roots, rhizomes and stems. Since ancient time, it has been regarded as one of top grade medicabecause of its safety and various medicinal properties. To further the development and utilization, a survey of patent information is very helpful to outline the current status of the drug. In this paper, Espacenetand World Traditional Medcine Patent Database were used to perform patent retrieval. Then the dataset were screened, standardized and analyzes via Python and R. The result indicates that, A . Senticosus, given being used for a long history, has less invention patents application comparing with other TCM drugs. The applications mainly come from China, Korea, Japan, Russia, and USA. The major functions includes systemic protection, anti-toxic agent, and treatments of nervous system, digestive system, metabolic, immune and allergic diseases. As to the compatibility of medicines, it often associated with tonic medicine, especially Buqi medicine.