CAJ | 학술논문

目的：了解我院鲍曼不动杆菌的分布和耐药情况，为临床治疗和预防提供依据。方法：采用Whonet 5.6软件对我院2012-2013年临床分离的351株鲍曼不动杆菌的分布及药敏试验结果进行分析。结果：鲍曼不动杆菌主要来源于痰标本（80.06%），主要分布在ICU（49.32%）；其耐药率除头孢哌酮-舒巴坦小于40%以外，对氨苄西林-舒巴坦、哌拉西林-他唑巴坦、头孢他啶、头孢吡肟、亚胺培南、环丙沙星等常用抗菌药的耐药率超过了60%。结论：鲍曼不动杆菌耐药性高，临床应根据药敏试验结果合理选择抗菌药物；加强耐药菌监测与控制管理乃当务之急。
목적：료해아원포만불동간균적분포화내약정황，위림상치료화예방제공의거。방법：채용Whonet 5.6연건대아원2012-2013년림상분리적351주포만불동간균적분포급약민시험결과진행분석。결과：포만불동간균주요래원우담표본（80.06%），주요분포재ICU（49.32%）；기내약솔제두포고동-서파탄소우40%이외，대안변서림-서파탄、고랍서림-타서파탄、두포타정、두포필우、아알배남、배병사성등상용항균약적내약솔초과료60%。결론：포만불동간균내약성고，림상응근거약민시험결과합리선택항균약물；가강내약균감측여공제관리내당무지급。
Objective:To understand the clinical distribution and drug resistance situation ofAcinetobacterbau-manniiin our hospital so as to provide a basis for clinical treatment and prevention.Methods:Using Whonet 5.6 software the distribution of 351 strains ofAcinetobacterbaumanniiisolated in our hospital from 2012 to 2013 and drug susceptibility results were analyzed.Results:Acinetobacterbaumanniicollected from sputum specimens(80.06%) was mainly distributed in the ICU(49.32%), and its drug resistance rate to ampicillin-sulbactam, piperacillin-tazobac-tam, ceftazidime, cefepime, imipenem, ciprofloxacin and other commonly used antibiotics was all more than 60%, but to cefoperazone-sulbactam sodium was less than 40%.Conclusion:Owing to the high resistance ofAcinetobac-terbaumannii, the antibacterials in clinical use should be selected reasonably according to the results of drug sensi-tivity. To strengthen the monitoring and control of drug resistance bacteria is a pressing matter of the moment.