CAJ | 학술논문

胃食管反流病（ GERD）是由下食管括约肌（ LES）功能不全导致胃、十二指肠内容物反流入食管引起不适症状和（或）并发症的一种疾病。目前GERD的主要治疗方法是药物和外科手术，但GERD患者多数需长期服药、且外科术后并发症较多。内镜技术是治疗GERD的微创方法，可安全、有效改善GERD症状，特别是Stretta 射频治疗、内镜下经口无创胃底折叠术（ TIF）以及LinX抗反流系统等。本文就内镜技术在治疗GERD中的研究进展作一综述。
위식관반류병（ GERD）시유하식관괄약기（ LES）공능불전도치위、십이지장내용물반류입식관인기불괄증상화（혹）병발증적일충질병。목전GERD적주요치료방법시약물화외과수술，단GERD환자다수수장기복약、차외과술후병발증교다。내경기술시치료GERD적미창방법，가안전、유효개선GERD증상，특별시Stretta 사빈치료、내경하경구무창위저절첩술（ TIF）이급LinX항반류계통등。본문취내경기술재치료GERD중적연구진전작일종술。
Gastroesophageal reflux disease( GERD)is caused by dysfunction of lower esophageal sphincter( LES), which allows the contents of stomach and duodenum to reflux into esophagus. Currently,medical and surgical therapies are the main treatment for GERD,but patients need to take life-long acid suppression and the surgical treatment has the risks of potential side effects. Endolumenal therapy as a minimally invasive approach to GERD can safely and effectively relieve the symptoms of GERD,especially Stretta radiofrequency procedure,transoral noninvasive fundoplication( TIF ) and LinX reflux management system. This article reviewed the advances in study on endolumenal therapy for GERD.