CAJ | 학술논문

目的：观察肾康注射液对维持性血液透析患者残余肾功能的保护作用。方法选取我院血液透析中心2012年1月至2013年12月行维持性血液透析患者60例,随机分为治疗组和对照组。治疗组在常规血液透析基础上加用肾康注射液治疗,疗程4周,治疗前后观察治疗前后患者24h 尿量、血肌酐(SCr)、尿素氮(BUN)、胱抑素 C,计算残余肾功能。结果治疗组治疗前后24h 尿量无明显变化(P >0．05),对照组治疗后24h 尿量有明显减少(P <0．05)；治疗组治疗后血肌酐、尿素氮、胱抑素 C 较治疗前均有降低(P <0．05),对照组降低不明显(P >0．05)。治疗组治疗后 RRF 较治疗前略升高(P >0．05),对照组 RRF 治疗后有明显下降(P <0．05)。结论使用肾康注射液治疗维持性血液透析患者,可有效保护患者残余肾功能,增加尿量,改善患者生存质量及预后。
목적：관찰신강주사액대유지성혈액투석환자잔여신공능적보호작용。방법선취아원혈액투석중심2012년1월지2013년12월행유지성혈액투석환자60례,수궤분위치료조화대조조。치료조재상규혈액투석기출상가용신강주사액치료,료정4주,치료전후관찰치료전후환자24h 뇨량、혈기항(SCr)、뇨소담(BUN)、광억소 C,계산잔여신공능。결과치료조치료전후24h 뇨량무명현변화(P >0．05),대조조치료후24h 뇨량유명현감소(P <0．05)；치료조치료후혈기항、뇨소담、광억소 C 교치료전균유강저(P <0．05),대조조강저불명현(P >0．05)。치료조치료후 RRF 교치료전략승고(P >0．05),대조조 RRF 치료후유명현하강(P <0．05)。결론사용신강주사액치료유지성혈액투석환자,가유효보호환자잔여신공능,증가뇨량,개선환자생존질량급예후。
Objective To observe the impact of Shenkang injection on residual renal function(RRF) in Hemodialysis pa-tients. Methods Sixtyhemodialysis patients were randomly divided into study group and control group. The two groups were given maintenancehemodialysis treatment. The study group were given with Shenkang injection plus. The period of treatment is 4 weeks. Before and after treatment,Serum creatinine,BUN,cystatin-C and daily urine output were detected and compared. And RRF was figured by the formula. Results After treatment,the study group’s daily urine output and RRF have no statistical differences com-pared with that of before treatment(P > 0. 05). The control group’s daily urine output and RRF have all reduced with statistical differences (P < 0. 05). SCr,BUN and cys-C in the study grouphave decrease after treatment(P < 0. 05),and in the control group there is no statistical differences between before and after treatment. Conclusion Shenkang injection can delay the speed of daily urine output reduction and protect RRF to some extent.