甘肃医药
甘肅醫藥
감숙의약
Gansu Medical Journal
2014年
12期
894-897
,共4页
张倩%徐金凤%孙薇%杨建波%魏建刚%张震中
張倩%徐金鳳%孫薇%楊建波%魏建剛%張震中
장천%서금봉%손미%양건파%위건강%장진중
脑梗死恢复期%健脑通络膏方%有效性%安全性
腦梗死恢複期%健腦通絡膏方%有效性%安全性
뇌경사회복기%건뇌통락고방%유효성%안전성
convalescent of cerebral infarction%Jiannao Tongluo paste%effectiveness%safety
目的：观察健脑通络膏方对脑梗死恢复期患者治疗的临床疗效及安全性。方法：收集新疆医科大学附属中医医院脑病二科2010年1月至2013年12月收治的60例既符合中医中风病肝肾亏虚兼痰瘀阻络证，又符合西医脑梗死的诊断标准、病程>2~4周、不伴意识障碍的动脉粥样硬化性血栓性脑梗死患者。将60例患者随机分为治疗组（健脑通络膏方组）与对照组。每组30例，对照组采用西医规范化治疗，治疗组在对照组用药基础上加用健脑通络膏方，两组疗程均为28天。两组分别于治疗前后行血常规、尿常规、粪常规、肝功、肾功、心电图，观察治疗前后中风病中医证候评分、美国国立卫生研究院卒中量表（NIHSS）评分、日常生活活动能力（Barthel指数）的变化。结果：健脑通络膏方治疗组和对照组治疗前后中风病中医证候评分、NIHSS评分、日常生活活动能力（Barthel指数）均有一定程度的改善，在以治疗组改善程度更为明显，且有统计学意义（P＜0.05），两组均无死亡病例，无发生明显的不良事件和不良反应。结论：健脑通络膏方治疗脑梗死恢复期患者有较好的疗效，未见明显不良反应。
目的：觀察健腦通絡膏方對腦梗死恢複期患者治療的臨床療效及安全性。方法：收集新疆醫科大學附屬中醫醫院腦病二科2010年1月至2013年12月收治的60例既符閤中醫中風病肝腎虧虛兼痰瘀阻絡證，又符閤西醫腦梗死的診斷標準、病程>2~4週、不伴意識障礙的動脈粥樣硬化性血栓性腦梗死患者。將60例患者隨機分為治療組（健腦通絡膏方組）與對照組。每組30例，對照組採用西醫規範化治療，治療組在對照組用藥基礎上加用健腦通絡膏方，兩組療程均為28天。兩組分彆于治療前後行血常規、尿常規、糞常規、肝功、腎功、心電圖，觀察治療前後中風病中醫證候評分、美國國立衛生研究院卒中量錶（NIHSS）評分、日常生活活動能力（Barthel指數）的變化。結果：健腦通絡膏方治療組和對照組治療前後中風病中醫證候評分、NIHSS評分、日常生活活動能力（Barthel指數）均有一定程度的改善，在以治療組改善程度更為明顯，且有統計學意義（P＜0.05），兩組均無死亡病例，無髮生明顯的不良事件和不良反應。結論：健腦通絡膏方治療腦梗死恢複期患者有較好的療效，未見明顯不良反應。
목적：관찰건뇌통락고방대뇌경사회복기환자치료적림상료효급안전성。방법：수집신강의과대학부속중의의원뇌병이과2010년1월지2013년12월수치적60례기부합중의중풍병간신우허겸담어조락증，우부합서의뇌경사적진단표준、병정>2~4주、불반의식장애적동맥죽양경화성혈전성뇌경사환자。장60례환자수궤분위치료조（건뇌통락고방조）여대조조。매조30례，대조조채용서의규범화치료，치료조재대조조용약기출상가용건뇌통락고방，량조료정균위28천。량조분별우치료전후행혈상규、뇨상규、분상규、간공、신공、심전도，관찰치료전후중풍병중의증후평분、미국국립위생연구원졸중량표（NIHSS）평분、일상생활활동능력（Barthel지수）적변화。결과：건뇌통락고방치료조화대조조치료전후중풍병중의증후평분、NIHSS평분、일상생활활동능력（Barthel지수）균유일정정도적개선，재이치료조개선정도경위명현，차유통계학의의（P＜0.05），량조균무사망병례，무발생명현적불량사건화불량반응。결론：건뇌통락고방치료뇌경사회복기환자유교호적료효，미견명현불량반응。
Objective:To observe effectiveness and safety of Jiannao Tongluo paste for convalescent of cerebral infarction. Methods:60 patients with disturbance of consciousness and arteriosclerotic thrombotic cerebral infarction (ATCI) were collected from encephalopathy department in affiliated hospital of Xinjiang medical university of TCM between Jan 2010 and Dec 2013 , according to the criterion with traditional Chinese and western medicine . 60 cases were randomly divided into treatment group (Jiannao Tongluo cream party group) and control group, with 30 cases in each group. Control group were adopted western medicine treatment and treatment group were used Jiannao Tongluo paste and western medicine treatment for 28 days . A complete blood count (CBC), urinalysis, stool sample examination, liver function tests (LFT), renal function tests, X-ray, electrocardiogram, TCM syndrome grade, national institute of health stroke scale (NIHSS) and activities of daily living (ADL) were observed before and after treatment. Results: There were significant difference between treatment group and control group in TCM syndrome grade , NIHSS and ADL (P<0.05). Recurrence rate of stroke in treatment group was significantly lower than control group(P<0.05). There were no dead and adverse reaction in each group. Conclusion:Jiannao Tongluo paste may be safety and effective for convalescent of cerebral infarction.
