风湿病与关节炎
風濕病與關節炎
풍습병여관절염
Rheumatism and Arthritis
2014年
12期
26-29
,共4页
急性痛风性关节炎%通痹祛湿方%临床观察%中医药
急性痛風性關節炎%通痺祛濕方%臨床觀察%中醫藥
급성통풍성관절염%통비거습방%림상관찰%중의약
acute gouty arthritis%Tongbi Qushi Prescription%clinical observation%TCM
目的:观察通痹祛湿方治疗急性痛风性关节炎的临床疗效。方法:将240例急性痛风性关节炎患者随机分为治疗组和对照组,每组120例。治疗组采用通痹祛湿方治疗,对照组采用秋水仙碱片治疗,两组均以14 d为1个疗程。观察两组患者关节疼痛、红肿、活动受限等临床症状及尿酸、红细胞沉降率、C-反应蛋白、黄嘌呤氧化酶等实验室指标的改变情况。结果:治疗后,两组患者各时点临床疗效呈逐渐递增趋势,且治疗组较对照组递增明显,差异有统计学意义(P<0.05);两组患者关节疼痛、红肿及活动受限积分及实验室指标等较治疗前均有明显改善(P<0.05),两组比较,差异有统计学意义(P<0.05)。结论:通痹祛湿方对改善急性痛风性关节炎患者临床症状及降低实验室指标有明显疗效,且安全性较好。
目的:觀察通痺祛濕方治療急性痛風性關節炎的臨床療效。方法:將240例急性痛風性關節炎患者隨機分為治療組和對照組,每組120例。治療組採用通痺祛濕方治療,對照組採用鞦水仙堿片治療,兩組均以14 d為1箇療程。觀察兩組患者關節疼痛、紅腫、活動受限等臨床癥狀及尿痠、紅細胞沉降率、C-反應蛋白、黃嘌呤氧化酶等實驗室指標的改變情況。結果:治療後,兩組患者各時點臨床療效呈逐漸遞增趨勢,且治療組較對照組遞增明顯,差異有統計學意義(P<0.05);兩組患者關節疼痛、紅腫及活動受限積分及實驗室指標等較治療前均有明顯改善(P<0.05),兩組比較,差異有統計學意義(P<0.05)。結論:通痺祛濕方對改善急性痛風性關節炎患者臨床癥狀及降低實驗室指標有明顯療效,且安全性較好。
목적:관찰통비거습방치료급성통풍성관절염적림상료효。방법:장240례급성통풍성관절염환자수궤분위치료조화대조조,매조120례。치료조채용통비거습방치료,대조조채용추수선감편치료,량조균이14 d위1개료정。관찰량조환자관절동통、홍종、활동수한등림상증상급뇨산、홍세포침강솔、C-반응단백、황표령양화매등실험실지표적개변정황。결과:치료후,량조환자각시점림상료효정축점체증추세,차치료조교대조조체증명현,차이유통계학의의(P<0.05);량조환자관절동통、홍종급활동수한적분급실험실지표등교치료전균유명현개선(P<0.05),량조비교,차이유통계학의의(P<0.05)。결론:통비거습방대개선급성통풍성관절염환자림상증상급강저실험실지표유명현료효,차안전성교호。
Objective:To observe the clinical curative effect of Tongbi Qushi Prescription in the treatment of acute gouty arthritis.Methods:240 cases of acute gouty arthritis were randomly divided into a treatment group and a control group,120 cases in each.The treatment group was treated with Tongbi Qushi Prescription,while the control group with colchicine tablets for a course of 14 d.observing clinical symptoms of the two groups such as joint pain,swelling,limitation of activity and other laboratory index changes of uric acid,erythrocyte sedimentation rate,C-reactive protein and xanthine oxidase.Results:After treatment,the clinical efifcacy of the two groups was gradually increasing at each time point,and the treatment group increased more obviously than the control group,the difference being statistically signiifcant(P<0.05);the joint pain,swelling and limitation of activity score and laboratory indicators of the two groups improved more signiifcantly than those before treatment(P<0.05),the difference between the two groups being statistically signiifcant(P<0.05). Conclusion:Tongbi Qushi Prescription can obviously improve clinical symptoms and decrease laboratory indexes of acute gouty arthritis,effective and safe.