CAJ | 학술논문

目的：通过对湛江市广东医学院附属医院骨科住院治疗诊断为骨质疏松患者的调查分析，为预防骨质疏松性骨折的发生提供理论依据。方法年龄在40岁以上的中老年人，均为久居本地区，2012年8月至2014年2月到广东医学院附属医院骨科住院治疗的骨质疏松者，调查内容包括一般情况调查、医学检查、静脉血检测及骨密度检测。结果骨折组平均年龄大于非骨折组；非骨折组腰椎骨密度（LSBMD）和股骨颈骨密度（FNBMD）的 T、Z 值和血清钙水平大于骨折组并且差异均有统计学意义（P＜0.05）。骨折组内以性别分成两组进行对比，其中女性年龄大于男性且差异有统计学意义（P ＜0.05），男性 LSBMD 的 T 和 Z值和 FNBMD T 值大于女性且差异有统计学意义（P ＜0.05）。按10岁为一年龄段分组，分析各年龄组中骨折与非骨折例数，＞70～80岁组骨折患者最多；分析各年龄组 LSBMD、FNBMD、血清钙和维生素 D 水平，非骨折组高于骨折组（P ＜0.05）。通过对骨折的影响因素进行非条件 Logistic 回归分析，明确年龄、腰椎骨密度、股骨颈骨密度 T 值升高是骨折的危险因素，而维生素 D、股骨颈骨密度、腰椎骨密度 T 值升高是骨折的保护因素。结论骨质疏松需及早预防，尤其在40岁以前进行，尽量提高骨密度峰值，防止日后出现骨质疏松症。
목적：통과대담강시엄동의학원부속의원골과주원치료진단위골질소송환자적조사분석，위예방골질소송성골절적발생제공이론의거。방법년령재40세이상적중노년인，균위구거본지구，2012년8월지2014년2월도엄동의학원부속의원골과주원치료적골질소송자，조사내용포괄일반정황조사、의학검사、정맥혈검측급골밀도검측。결과골절조평균년령대우비골절조；비골절조요추골밀도（LSBMD）화고골경골밀도（FNBMD）적 T、Z 치화혈청개수평대우골절조병차차이균유통계학의의（P＜0.05）。골절조내이성별분성량조진행대비，기중녀성년령대우남성차차이유통계학의의（P ＜0.05），남성 LSBMD 적 T 화 Z치화 FNBMD T 치대우녀성차차이유통계학의의（P ＜0.05）。안10세위일년령단분조，분석각년령조중골절여비골절례수，＞70～80세조골절환자최다；분석각년령조 LSBMD、FNBMD、혈청개화유생소 D 수평，비골절조고우골절조（P ＜0.05）。통과대골절적영향인소진행비조건 Logistic 회귀분석，명학년령、요추골밀도、고골경골밀도 T 치승고시골절적위험인소，이유생소 D、고골경골밀도、요추골밀도 T 치승고시골절적보호인소。결론골질소송수급조예방，우기재40세이전진행，진량제고골밀도봉치，방지일후출현골질소송증。
Objective Through the research and analysis of guangdong medical college affiliated hospital orthopaedic hospitalized patients with a diagnosis of osteoporosis in Zhanjiang,this paper provide theoretical basis for the prevention of osteoporosis frac-ture.Methods The elderly aged over 40 years old,living in this area for a long time.Data was collected from August 2012 to Feb-ruary 2014,hospitalized patients in guangdong medical college affiliated hospital were diagnosed with osteoporosis.Contents include general situation survey,medical examination,venous blood tests and bone mineral density testing.Results Fracture group average age is older than the non fracture group;the fracture group lumbar spine bone mineral density(LSBMD)and femoral neck bone min-eral density(FNBMD)T value and Z value and serum calcium group is greater than the fracture and the differences were statistically significant(P <0.05).Fracture group in gender divided into two groups for comparison,in which women older than men,and the difference was statistically significant(P <0.05),male LSBMD T and Z values and FNBMD T value is greater than the female and the difference was statistically significant(P <0.05).According to the 10 year age group,Each age group compared with the frac-ture number and non fracture number,in the age group of 70-80 fracture number were the most;All age groups in LSBMD,FNB-MD,serum calcium(Ca)and VitD compared,non fracture group is most higher than that of fracture group.The influence factors of the fractures for non conditional Logistic regression analysis,age,LSBMD,FNBMD T value increased were risk factors for fracture, VitD,FNBMD,LSBMD T value increased were protective factors of fracture.Conclusion Need as soon as possible to prevent osteo-porosis,especially before the age of 40,try to improve the peak bone density,to prevent the occurrence of osteoporosis in the future.