CAJ | 학술논문

目的：探讨益气养阴汤对围手术期胃癌患者细胞免疫功能的影响。方法选择胃癌根治术患者60例，随机方法分为实验组、对照组两组。两组分别于服药前1 d、术后第1天、第7天检测细胞免疫指标CD3+、CD4+、CD8+、CD4+/CD8+。结果术后第1天患者CD3+、CD4+、CD4+/CD8+比值均较术前有所下降，使用益气养阴汤患者术后第1天、术后第7天CD3+、CD4+、CD8+、CD4+/CD8+等细胞免疫指标恢复较快，与对照组比较差异有统计学意义（P<0.05），两组病人治疗期间均未出现严重并发症。结论益气养阴汤可明显增强围手术期胃癌患者细胞免疫功。
목적：탐토익기양음탕대위수술기위암환자세포면역공능적영향。방법선택위암근치술환자60례，수궤방법분위실험조、대조조량조。량조분별우복약전1 d、술후제1천、제7천검측세포면역지표CD3+、CD4+、CD8+、CD4+/CD8+。결과술후제1천환자CD3+、CD4+、CD4+/CD8+비치균교술전유소하강，사용익기양음탕환자술후제1천、술후제7천CD3+、CD4+、CD8+、CD4+/CD8+등세포면역지표회복교쾌，여대조조비교차이유통계학의의（P<0.05），량조병인치료기간균미출현엄중병발증。결론익기양음탕가명현증강위수술기위암환자세포면역공。
Objective To investigate the effect of Yiqi Yangyin Decoction on the cellular immunity of patients with gastric cancer during the perioperative period. Methods 60 patients underwent radical resection of gastric cancer were randomly divided into two groups, the experimental group and the control group. Cell immune indexes CD3+, CD4+, CD8+, CD4+/CD8+ were detected in both groups 1 day before taking the medicine, 1 day after the operation, 7 days after the operation. Results 1 day after the opera-tion, the CD3+, CD4+, CD4+/CD8+ ratio of the patients decreased compared with that before the operation. The CD3+, CD4+, CD8+, CD4+/CD8+ cellular immunity indexes of the patients who took Yiqi Yangyin Decoction recovered faster at the first day, 7th day after the operation as compared with those of the control group, the differences between the two groups were statistically significant (P<0.05). No severe complications occurred in both groups of patients during the period of treatment. Conclusion Yiqi Yangyin Decoction can significantly enhance the cellular immune function of patients with gastric cancer during the perioperative period.