中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2014年
33期
67-68
,共2页
慢性阻塞性肺疾病急性加重%糖化血红蛋白%血清降钙素原%C反应蛋白%D-二聚体
慢性阻塞性肺疾病急性加重%糖化血紅蛋白%血清降鈣素原%C反應蛋白%D-二聚體
만성조새성폐질병급성가중%당화혈홍단백%혈청강개소원%C반응단백%D-이취체
Acute exacerbation of chronic obstructive pulmonary disease%Glycosylated hemoglobin%Serum procalcitonin%C-re-active protein%D-dimer
目的：探讨分析糖化血红蛋白的测定对慢性阻塞性肺疾病急性加重的意义。方法选取2011年9月—2014年7月在该院就诊的慢性阻塞性肺疾病急性加重期病人（A组）32例，慢性阻塞性肺疾病稳定期病人（B组）50例，正常对照（C组）30例，分别测定其糖化血红蛋白、血清降钙素原、C反应蛋白和D-二聚体，探讨分析糖化血红蛋白对慢性阻塞性肺疾病急性加重的意义。结果 A组的糖化血红蛋白为（5.87±0.72）%， B组的糖化血红蛋白为（5.21±0.59）%， C组的糖化血红蛋白（5.14±0.52）%；A组血清降钙素原、C反应蛋白和D-二聚体分别为（2.81±1.21）ng/mL、（119.27±11.24）mg/L和（3.21±0.18）mg/L，B组的血清降钙素原、C反应蛋白和D-二聚体分别为（0.81±0.24）ng/mL、（9.48±3.27）mg/L和（0.57±0.21）mg/L， C组的血清降钙素原、C反应蛋白和D-二聚体分别为（0.59±0.23）ng/mL、（8.71±2.98）mg/L和（0.49±0.27）mg/L；A组的糖化血红蛋白、血清降钙素原、C反应蛋白和D-二聚体都明显高于B组和C组，且差异有统计学意义（P<0.05）。结论糖化血红蛋白、血清降钙素原、C反应蛋白和D-二聚体联合检测有助于早期判断慢性阻塞性肺疾病急性加重，有助于改善慢性阻塞性肺疾病的预后。
目的：探討分析糖化血紅蛋白的測定對慢性阻塞性肺疾病急性加重的意義。方法選取2011年9月—2014年7月在該院就診的慢性阻塞性肺疾病急性加重期病人（A組）32例，慢性阻塞性肺疾病穩定期病人（B組）50例，正常對照（C組）30例，分彆測定其糖化血紅蛋白、血清降鈣素原、C反應蛋白和D-二聚體，探討分析糖化血紅蛋白對慢性阻塞性肺疾病急性加重的意義。結果 A組的糖化血紅蛋白為（5.87±0.72）%， B組的糖化血紅蛋白為（5.21±0.59）%， C組的糖化血紅蛋白（5.14±0.52）%；A組血清降鈣素原、C反應蛋白和D-二聚體分彆為（2.81±1.21）ng/mL、（119.27±11.24）mg/L和（3.21±0.18）mg/L，B組的血清降鈣素原、C反應蛋白和D-二聚體分彆為（0.81±0.24）ng/mL、（9.48±3.27）mg/L和（0.57±0.21）mg/L， C組的血清降鈣素原、C反應蛋白和D-二聚體分彆為（0.59±0.23）ng/mL、（8.71±2.98）mg/L和（0.49±0.27）mg/L；A組的糖化血紅蛋白、血清降鈣素原、C反應蛋白和D-二聚體都明顯高于B組和C組，且差異有統計學意義（P<0.05）。結論糖化血紅蛋白、血清降鈣素原、C反應蛋白和D-二聚體聯閤檢測有助于早期判斷慢性阻塞性肺疾病急性加重，有助于改善慢性阻塞性肺疾病的預後。
목적：탐토분석당화혈홍단백적측정대만성조새성폐질병급성가중적의의。방법선취2011년9월—2014년7월재해원취진적만성조새성폐질병급성가중기병인（A조）32례，만성조새성폐질병은정기병인（B조）50례，정상대조（C조）30례，분별측정기당화혈홍단백、혈청강개소원、C반응단백화D-이취체，탐토분석당화혈홍단백대만성조새성폐질병급성가중적의의。결과 A조적당화혈홍단백위（5.87±0.72）%， B조적당화혈홍단백위（5.21±0.59）%， C조적당화혈홍단백（5.14±0.52）%；A조혈청강개소원、C반응단백화D-이취체분별위（2.81±1.21）ng/mL、（119.27±11.24）mg/L화（3.21±0.18）mg/L，B조적혈청강개소원、C반응단백화D-이취체분별위（0.81±0.24）ng/mL、（9.48±3.27）mg/L화（0.57±0.21）mg/L， C조적혈청강개소원、C반응단백화D-이취체분별위（0.59±0.23）ng/mL、（8.71±2.98）mg/L화（0.49±0.27）mg/L；A조적당화혈홍단백、혈청강개소원、C반응단백화D-이취체도명현고우B조화C조，차차이유통계학의의（P<0.05）。결론당화혈홍단백、혈청강개소원、C반응단백화D-이취체연합검측유조우조기판단만성조새성폐질병급성가중，유조우개선만성조새성폐질병적예후。
Objective To study and analyze the significance of determination of glycosylated hemoglobin for acute exacerbation of chronic obstructive pulmonary disease. Methods The determination of glycosylated hemoglobin, serum procalcitonin, C-reactive protein and D-dimer was performed in the 32 patients with acute exacerbation of chronic obstructive pulmonary disease (group A), 50 patients with chronic obstructive pulmonary disease at stable phase(group B) and 30 normal controls(group C) visited our hospi-tal from September 2011 to July 2014. And the significance of glycosylated hemoglobin for acute exacerbation of chronic obstruc-tive pulmonary disease was investigated and analyzed. Results The value of glycosylated hemoglobin was (5.87±0.72)%in group A, (5.21 ±0.59)% in group B, and (5.14 ±0.52)% in group C; the value of serum procalcitonin, C-reactive protein and D-dimer of group A was (2.81±1.21) ng/ml, (119.27±11.24) mg/l, (3.21±0.18) mg/l, that of group B was (0.81±0.24) ng/ml, (9.48±3.27) mg/l, (0.57±0.21) mg/l, respectively, and that of group C was (0.59±0.23) ng/ml, (8.71±2.98) mg/l, (0.49±0.27) mg/l, respectively, the value of glycosylated hemoglobin, serum procalcitonin, C-reactive protein and D-dimer of group A was obviously higher than that of group B and group C with statistically significant difference (P<0.05). Conclusion The combined detection of glycosylated hemoglobin, serum procalcitonin, C-reactive protein and D-dimer helps to early judge the acute exacerbation of chronic obstruc-tive pulmonary disease and is conducive to improving the prognosis of chronic obstructive pulmonary disease.
