CAJ | 학술논문

目的：探讨宫颈癌患者TK1及CA125对其诊断及治疗中的意义。方法联合检测50例宫颈癌患者、30例同期进行体检的健康妇女血清中TK1、CA125的含量，同时对宫颈癌患者在同期放化疗后再次测定TK1、CA125的含量并与治疗前进行比较。结果宫颈癌患者的TK1、CA125含量显著高于对照组（P<0.001），治疗后宫颈癌患者的TK1、CA125较治疗前显著下降（P<0.05）。结论 TK1、CA125的水平在宫颈癌的诊断、治疗及预后评估中有一定的价值。
목적：탐토궁경암환자TK1급CA125대기진단급치료중적의의。방법연합검측50례궁경암환자、30례동기진행체검적건강부녀혈청중TK1、CA125적함량，동시대궁경암환자재동기방화료후재차측정TK1、CA125적함량병여치료전진행비교。결과궁경암환자적TK1、CA125함량현저고우대조조（P<0.001），치료후궁경암환자적TK1、CA125교치료전현저하강（P<0.05）。결론 TK1、CA125적수평재궁경암적진단、치료급예후평고중유일정적개치。
Objective To investigate the value of serum thymidine kinase 1 (TK1) and cancer antigen 125(CA125) in the diagnosis and treatment of cervical cancer. Methods The combined detection of the content of serum TK1 and CA125 was performed in 50 cases with cervical cancer (the cervical cancer group) and 30 healthy controls (the control group) underwent physical examination over the same period. And for the patients with cervical cancer, after concurrent chemoradiotherapy, the content of TK1 and CA125 was measured again and the results were compared with those before treatment. Results The levels of TK1 and CA125 in the cervical cancer group were much higher than those in the control group (P<0.001). After treatment, the levels of TK1 and CA125 in the cervical cancer group declined significantly compared with those before treatment(P<0.05). Conclusion The levels of TK1 and CA125 have certain value in the diagnosis, treatment and evaluation of the prognosis of the cervical cancer.