CAJ | 학술논문

目的：研究抑郁症与甲状腺功能之间的相关性。方法采用化学发光法测定抑郁症组和正常对照组总三碘甲腺原氨酸(tt3)，总甲状腺素(tt4)，游离三碘甲腺原氨酸(ft3)，游离甲状腺素(ft4)，促甲状腺激素(tsH)的水平。结果抑郁症组与正常对照组血清甲状腺激素水平大部分在正常范围，但两组间比较抑郁症组 tt3，ft3，tsH 水平明显下降， ft4水平升高，具有统计学差异；抑郁症患者女性与男性血清甲状腺激素水平比较无明显差异(P>0.05)；统计抑郁症组低 t3综合征的发生率明显高于正常对照组。结论两组甲状腺功能有一定的差异，甲状腺激素水平与抑郁症患者的一些症状存在相关性，部分抑郁症患者的血清 ft3浓度明显下降，更易发生低 t3综合征。
목적：연구억욱증여갑상선공능지간적상관성。방법채용화학발광법측정억욱증조화정상대조조총삼전갑선원안산(tt3)，총갑상선소(tt4)，유리삼전갑선원안산(ft3)，유리갑상선소(ft4)，촉갑상선격소(tsH)적수평。결과억욱증조여정상대조조혈청갑상선격소수평대부분재정상범위，단량조간비교억욱증조 tt3，ft3，tsH 수평명현하강， ft4수평승고，구유통계학차이；억욱증환자녀성여남성혈청갑상선격소수평비교무명현차이(P>0.05)；통계억욱증조저 t3종합정적발생솔명현고우정상대조조。결론량조갑상선공능유일정적차이，갑상선격소수평여억욱증환자적일사증상존재상관성，부분억욱증환자적혈청 ft3농도명현하강，경역발생저 t3종합정。
Objective to study the correlation between depression and thyroid function. Methods chemiluminescence was introduced to detect the level of total three iodine thyronime(tt3), total thyroxice(tt4), free three iodine thyroxine(ft3), free thyroxine (ft4) and thyroid stimulating hormone(tsH) in depression group and normal control group. Results thyroid hormone in serum of both depression group and normal control group was mostly within normal range mostly, but the levels of TT3, FT3 and TSH in depression group were decreased significantly, while the level of FT4 increased. The difference was significant statistically. The difference of thyroid hormone in serum between female and male patients with depression was not significant (P>0.05). the incidence of low t3 syndrome is greatly higher than that of normal control group. Conclusion the thyroid function in two groups has certain difference. the level of thyroid hormone is correlated with the symptoms of patients with depression. FT3 concentrate in serum for some patients with depression is decreased significantly. These patients are more susceptible to low t3 syndrome.