世界最新医学信息文摘(连续型电子期刊)
世界最新醫學信息文摘(連續型電子期刊)
세계최신의학신식문적(련속형전자기간)
World Latest Medicine Information
2014年
32期
32-33
,共2页
小细胞肝癌%三维适形放疗%疗效
小細胞肝癌%三維適形放療%療效
소세포간암%삼유괄형방료%료효
small hepatocellular carcinoma%three-dimensional conformal radiotherapy%efficacy
目的:研究同步三维适形放疗联合化疗治疗小细胞肝癌的临床疗效。方法选取2013年1月到2014年6月,我院的100例小细胞肝癌患者的治疗案例进行回顾性分析,将患者根据治疗方案不同分为常规化疗组(a 组)和同步三维适形放疗联合化疗组(B 组)两组,分析两种方法的临床疗效。结果 a 组治疗小细胞肝癌患者的总有效率为61.67%(21/34),B 组治疗小细胞肝癌总有效率为80.30%(53/66),两组总有效率相比,差异具有统计学意义(P<0.05)。因此,同步三维适形放疗联合化疗治疗方法在治疗的总有效率方面明显高于常规化疗组。a 组小细胞肝癌患者的不良反应发生率为23.53%(8/34),B 组小细胞肝癌患者不良反应发生率为21.21%(14/66),通过对两组不良反应发生率的比较,发现不良反应发生率的差异无统计学意义(P >0.05);a 组的患者对治疗的满意度为58.82%(20/34),B组的患者对治疗的满意度为81.82%(54/66),通过对两组患者满意度对比,发现两组患者的满意度的差异具有统计学意义(P<0.05)。因此,三维适形放疗联合化疗组治疗小细胞肝癌患者的患者满意度明显高于常规化疗组,在不良反应发生率方面相差不大。结论同步三维适形放疗联合化疗治疗小细胞肝癌的临床有效率比常规化疗治疗有效率更高,患者对治疗效果更满意。
目的:研究同步三維適形放療聯閤化療治療小細胞肝癌的臨床療效。方法選取2013年1月到2014年6月,我院的100例小細胞肝癌患者的治療案例進行迴顧性分析,將患者根據治療方案不同分為常規化療組(a 組)和同步三維適形放療聯閤化療組(B 組)兩組,分析兩種方法的臨床療效。結果 a 組治療小細胞肝癌患者的總有效率為61.67%(21/34),B 組治療小細胞肝癌總有效率為80.30%(53/66),兩組總有效率相比,差異具有統計學意義(P<0.05)。因此,同步三維適形放療聯閤化療治療方法在治療的總有效率方麵明顯高于常規化療組。a 組小細胞肝癌患者的不良反應髮生率為23.53%(8/34),B 組小細胞肝癌患者不良反應髮生率為21.21%(14/66),通過對兩組不良反應髮生率的比較,髮現不良反應髮生率的差異無統計學意義(P >0.05);a 組的患者對治療的滿意度為58.82%(20/34),B組的患者對治療的滿意度為81.82%(54/66),通過對兩組患者滿意度對比,髮現兩組患者的滿意度的差異具有統計學意義(P<0.05)。因此,三維適形放療聯閤化療組治療小細胞肝癌患者的患者滿意度明顯高于常規化療組,在不良反應髮生率方麵相差不大。結論同步三維適形放療聯閤化療治療小細胞肝癌的臨床有效率比常規化療治療有效率更高,患者對治療效果更滿意。
목적:연구동보삼유괄형방료연합화료치료소세포간암적림상료효。방법선취2013년1월도2014년6월,아원적100례소세포간암환자적치료안례진행회고성분석,장환자근거치료방안불동분위상규화료조(a 조)화동보삼유괄형방료연합화료조(B 조)량조,분석량충방법적림상료효。결과 a 조치료소세포간암환자적총유효솔위61.67%(21/34),B 조치료소세포간암총유효솔위80.30%(53/66),량조총유효솔상비,차이구유통계학의의(P<0.05)。인차,동보삼유괄형방료연합화료치료방법재치료적총유효솔방면명현고우상규화료조。a 조소세포간암환자적불량반응발생솔위23.53%(8/34),B 조소세포간암환자불량반응발생솔위21.21%(14/66),통과대량조불량반응발생솔적비교,발현불량반응발생솔적차이무통계학의의(P >0.05);a 조적환자대치료적만의도위58.82%(20/34),B조적환자대치료적만의도위81.82%(54/66),통과대량조환자만의도대비,발현량조환자적만의도적차이구유통계학의의(P<0.05)。인차,삼유괄형방료연합화료조치료소세포간암환자적환자만의도명현고우상규화료조,재불량반응발생솔방면상차불대。결론동보삼유괄형방료연합화료치료소세포간암적림상유효솔비상규화료치료유효솔경고,환자대치료효과경만의。
Objective To study the clinical efficacy of synchronized three-dimensional conformal radiotherapy combined with chemotherapy in treatment of small hepatocellular carcinoma. Methods the data of 100 cases of patients with small hepatocellular carcinoma selected from January 2013 to June 2014 in our hospital, were retrospectively analyzed. these patients were divided into conventional chemotherapy group (a) and synchronous three-dimensional conformal radiotherapy combined with chemotherapy (group B) group, according to the different therapeutic schedule. then the clinical efficacy of the two kinds of methods were analyzed.Results the total effective rate was 61.67% (21/34) in group a, while the rate was 80.30%(53/66) in group B. Compared with the rate in two groups, there was statistically significant difference (P<0.05). Therefore, the synchronous three-dimensional conformal radiotherapy combined with chemotherapy treatments in terms of total efficiency of treatment was significantly higher than that in the conventional chemotherapy group. The adverse reactions incidence rate was 23.53% (8/34) in group a and that rate was 21.21% (14/66) in group B. By comparing the incidence of adverse reactions in the two groups, there was no statistically significant difference (P> 0.05). The patients' satisfaction in group A was 58.82% (20/34), and patients satisfaction in group B was 81.82% (54 / 66), by comparing patient satisfaction of two groups, there was statistically significant difference (P <0.05). therefore, the patient satisfaction in three-dimensional conformal radiotherapy combined with chemotherapy treatment group was significantly higher than that in conventional chemotherapy group. And there was no significance in terms of incidence of adverse reactions. Conclusion synchronous three-dimensional conformal radiotherapy combined with chemotherapy in clinical treatment of small hepatocellular carcinoma has higher effective rate than conventional chemotherapy treatment and patients satisfaction treated by this kind of therapy is much higher.