中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
35期
1-2
,共2页
复合乳酸菌胶囊%肝硬化%小肠细菌过生长%血氨
複閤乳痠菌膠囊%肝硬化%小腸細菌過生長%血氨
복합유산균효낭%간경화%소장세균과생장%혈안
Lactobacillus Complex Capsules%Cirrhosis%SIBO%Plasma ammonia
目的：探讨复合乳酸菌胶囊治疗肝硬化患者的小肠细菌过度生长及血氨的有效性。方法：选取笔者所在医院2012年6月-2013年12月收治的80例乙肝肝硬化伴有SIBO的患者，按照随机数字表法将其分为治疗组和对照组各40例，对照组给予常规药物治疗，治疗组在常规治疗基础上给予复合乳酸菌胶囊0.66 g/次，口服，3次/d，疗程均为4周。观察比较两组患者的临床疗效及治疗前后血氨浓度变化。结果：治疗4周后，治疗组的治疗有效率77.5%(31/40)明显高于对照组的27.5%(11/40)，差异有统计学意义(P<0.05)。两组治疗4周后的血氨水平均明显低于治疗前，且治疗组的血氨水平(42.7±10.3)μmol/L明显低于对照组的(76.6±8.5)μmol/L，差异均有统计学意义(P<0.05)。结论：复合乳酸菌胶囊对肝硬化患者的小肠细菌过度生长有显著疗效，且能显著降低血氨水平，值得临床推广使用。
目的：探討複閤乳痠菌膠囊治療肝硬化患者的小腸細菌過度生長及血氨的有效性。方法：選取筆者所在醫院2012年6月-2013年12月收治的80例乙肝肝硬化伴有SIBO的患者，按照隨機數字錶法將其分為治療組和對照組各40例，對照組給予常規藥物治療，治療組在常規治療基礎上給予複閤乳痠菌膠囊0.66 g/次，口服，3次/d，療程均為4週。觀察比較兩組患者的臨床療效及治療前後血氨濃度變化。結果：治療4週後，治療組的治療有效率77.5%(31/40)明顯高于對照組的27.5%(11/40)，差異有統計學意義(P<0.05)。兩組治療4週後的血氨水平均明顯低于治療前，且治療組的血氨水平(42.7±10.3)μmol/L明顯低于對照組的(76.6±8.5)μmol/L，差異均有統計學意義(P<0.05)。結論：複閤乳痠菌膠囊對肝硬化患者的小腸細菌過度生長有顯著療效，且能顯著降低血氨水平，值得臨床推廣使用。
목적：탐토복합유산균효낭치료간경화환자적소장세균과도생장급혈안적유효성。방법：선취필자소재의원2012년6월-2013년12월수치적80례을간간경화반유SIBO적환자，안조수궤수자표법장기분위치료조화대조조각40례，대조조급여상규약물치료，치료조재상규치료기출상급여복합유산균효낭0.66 g/차，구복，3차/d，료정균위4주。관찰비교량조환자적림상료효급치료전후혈안농도변화。결과：치료4주후，치료조적치료유효솔77.5%(31/40)명현고우대조조적27.5%(11/40)，차이유통계학의의(P<0.05)。량조치료4주후적혈안수평균명현저우치료전，차치료조적혈안수평(42.7±10.3)μmol/L명현저우대조조적(76.6±8.5)μmol/L，차이균유통계학의의(P<0.05)。결론：복합유산균효낭대간경화환자적소장세균과도생장유현저료효，차능현저강저혈안수평，치득림상추엄사용。
Objective:To investigate the effectiveness of Lactobacillus Complex Capsules on SIBO and plasma ammonia of the patients with cirrhosis. Method:80 hepatitis B cirrhosis patients with ISBO positive in our hospital from June 2012 to December 2013 were selected,they were randomly divided into the control group and the treatment group,40 cases in each group.The control group was given conventional drugs treatment,the treatment group was given Lactobacillus Complex Capsules on the basis of conventional therapy,0.66 g/time,took orally,three times a day,the course of treatment was 4 weeks.The clinical effect and changes of plasma ammonia concentration before and after treatment.Result:After 4 weeks treatment,the total effective rate of treatment group was 77.5%(31/40),it was significantly higher than 27.5%(11/40) of control group,the difference was statistically significant(P<0.05).The level of plasma ammonia after 4 weeks treatment in two groups were significantly lower than before treatment,the level of plasma ammonia in treatment group was (42.7±10.3)μmol/L,it was significantly lower than (76.6±8.5)μmol/L,the differences were statistically significant(P<0.05).Conclusion:Lactobacillus Complex Capsules on cirrhotic patients with SIBO has remarkable curative effect,and can reduce the levels of plasma ammonia,is worthy of clinical use.
