CAJ | 학술논문

目的探讨前哨淋巴结活检在cN0口腔鳞状细胞癌治疗中的可行性、准确性。方法对20例cN0口腔鳞状细胞癌患者术前使用核素扫描法行前哨淋巴结示综，体表定位；术中r原探测仪垣亚甲蓝染色进一步识别前哨淋巴结，行前哨淋巴结活检，同时行颈部淋巴清扫，术后对前哨淋巴结和颈部非前哨淋巴结的病理检查结果进行分析。结果20例cN0口腔癌患者共检测出38枚前哨淋巴结，前哨淋巴结检测率100%，常规病理检查阳性率(21枚/38枚)55.3%，另外17枚阴性前哨淋巴结加行免疫组化(CK法)检查阳性率(2枚/17枚)11.8%。结论前哨淋巴结活检是cN0口腔鳞状细胞癌治疗中的一项新技术，能较准确地反映颈部淋巴结状态，具有一定的临床实用性。
목적탐토전초림파결활검재cN0구강린상세포암치료중적가행성、준학성。방법대20례cN0구강린상세포암환자술전사용핵소소묘법행전초림파결시종，체표정위；술중r원탐측의원아갑람염색진일보식별전초림파결，행전초림파결활검，동시행경부림파청소，술후대전초림파결화경부비전초림파결적병리검사결과진행분석。결과20례cN0구강암환자공검측출38매전초림파결，전초림파결검측솔100%，상규병리검사양성솔(21매/38매)55.3%，령외17매음성전초림파결가행면역조화(CK법)검사양성솔(2매/17매)11.8%。결론전초림파결활검시cN0구강린상세포암치료중적일항신기술，능교준학지반영경부림파결상태，구유일정적림상실용성。
Objective To explore the feasibility and reliability of sentinel lymph node biopsy in the treatment of cN0 oral squamous cel carcinoma. Methods Radionuclide scanning was used to trace and locate the sentinel lymph node in 20 patients with cN0 oral squamous cel carcinoma before operation. And during surgery, sentinel lymph node biopsy and cervical dissection were conducted after the sentinel lymph node had been further identified by using γ-detector and methylene blue staining. At last, the sentinel lymph node and non-sentinel lymph nodes of the neck were pathological y diagnosed and analyzed after operation. Results Al of the 20 patients of cN0 oral cancer were detected to be with sentinel lymph node (in total 38 pieces). 21 of the 38 sentinel lymph nodes (55.3%) were found to be with cancer cel matastasis by routine pathological examination. The other 17 negative nodes were put into immunohistochemistry staining (CK) and 2 were confirmed to be positive (11.8%). Conclusion As a newtechnique in the treatment of oral squamous cel carcinoma, sentinel lymph node biopsy is able to accurately reflect the status of cervical lymph node and is with certain value of clinical application.