中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
36期
1-3,4
,共4页
丁芹%王莉娜%潘玉%宋正霞%颜学兵
丁芹%王莉娜%潘玉%宋正霞%顏學兵
정근%왕리나%반옥%송정하%안학병
布鲁菌病%回顾性分析%诊断%治疗
佈魯菌病%迴顧性分析%診斷%治療
포로균병%회고성분석%진단%치료
Brucellosis%Retrospective studies%Diagnosis%Therapeutics
目的：分析徐州地区布鲁菌病的流行情况、临床症状、体征、化验检查及治疗情况。方法：回顾分析徐州医学院附属医院2011年1月-2014年7月收治的30例布鲁菌病病例的临床资料，包括一般资料、主要临床表现、实验室检查、用药情况及疗效。结果：本地区布鲁菌病发病例数逐年增加，以冬春季节多见；发病人群以中青年男性为主，多有羊接触史；临床主要表现为发热(100%)、骨关节疼痛(73.3%)、多汗(53.3%)及乏力(40.0%)，部分患者可出现肌肉疼痛(26.7%)、淋巴结肿大(20.0%)、败血症(16.7%)、肺炎(13.3%)、肝脾肿大(10.0%)、胸腔积液(10.0%)、皮疹(6.7%)。典型波状热仅有11例(36.7%)。多数患者血常规、肝功能无明显异常，血沉增快23例(76.7%)，影像学检查证实骨关节病变8例(36.4%)。只有2例(6.7%)首诊得到确诊。治疗主要采用多西环素、利福平及左氧氟沙星联合，27例在2周内体温恢复正常。结论：徐州地区布鲁菌病散发病例有逐年增多的趋势，临床表现不典型，易误诊，应重视流行病学线索，加强对布鲁菌病的认识。采用多西环素、利福平及左氧氟沙星联合治疗效果较好。
目的：分析徐州地區佈魯菌病的流行情況、臨床癥狀、體徵、化驗檢查及治療情況。方法：迴顧分析徐州醫學院附屬醫院2011年1月-2014年7月收治的30例佈魯菌病病例的臨床資料，包括一般資料、主要臨床錶現、實驗室檢查、用藥情況及療效。結果：本地區佈魯菌病髮病例數逐年增加，以鼕春季節多見；髮病人群以中青年男性為主，多有羊接觸史；臨床主要錶現為髮熱(100%)、骨關節疼痛(73.3%)、多汗(53.3%)及乏力(40.0%)，部分患者可齣現肌肉疼痛(26.7%)、淋巴結腫大(20.0%)、敗血癥(16.7%)、肺炎(13.3%)、肝脾腫大(10.0%)、胸腔積液(10.0%)、皮疹(6.7%)。典型波狀熱僅有11例(36.7%)。多數患者血常規、肝功能無明顯異常，血沉增快23例(76.7%)，影像學檢查證實骨關節病變8例(36.4%)。隻有2例(6.7%)首診得到確診。治療主要採用多西環素、利福平及左氧氟沙星聯閤，27例在2週內體溫恢複正常。結論：徐州地區佈魯菌病散髮病例有逐年增多的趨勢，臨床錶現不典型，易誤診，應重視流行病學線索，加彊對佈魯菌病的認識。採用多西環素、利福平及左氧氟沙星聯閤治療效果較好。
목적：분석서주지구포로균병적류행정황、림상증상、체정、화험검사급치료정황。방법：회고분석서주의학원부속의원2011년1월-2014년7월수치적30례포로균병병례적림상자료，포괄일반자료、주요림상표현、실험실검사、용약정황급료효。결과：본지구포로균병발병례수축년증가，이동춘계절다견；발병인군이중청년남성위주，다유양접촉사；림상주요표현위발열(100%)、골관절동통(73.3%)、다한(53.3%)급핍력(40.0%)，부분환자가출현기육동통(26.7%)、림파결종대(20.0%)、패혈증(16.7%)、폐염(13.3%)、간비종대(10.0%)、흉강적액(10.0%)、피진(6.7%)。전형파상열부유11례(36.7%)。다수환자혈상규、간공능무명현이상，혈침증쾌23례(76.7%)，영상학검사증실골관절병변8례(36.4%)。지유2례(6.7%)수진득도학진。치료주요채용다서배소、리복평급좌양불사성연합，27례재2주내체온회복정상。결론：서주지구포로균병산발병례유축년증다적추세，림상표현불전형，역오진，응중시류행병학선색，가강대포로균병적인식。채용다서배소、리복평급좌양불사성연합치료효과교호。
Objective:To investigate the epidemiological,clinical,laboratory and treatment data of brucellosis in Xuzhou.Method:The prevalence, symptoms and signs,laboratory,treatment and outcome data of 30 brucellosis patients admitted in affiliated hospital of Xuzhou Medical College from January 2011 to July 2014 were retrospectively analyzed.Result:The cases of brucellosis were increased gradually in Xuzhou,which were more frequent in winter and spring.The patients were mainly middle-aged males,and most of them had a history of close contact with sheep.The main clinical manifestations were fever(100%), arthralgia(73.3%),sweating(53.3%) and fatigue (40.0%).Some patients had myalgia(26.7%),sepsis(16.7%),pneumonia(13.3%),hepatomegaly and splenomegaly(10.0%),pleural effusion(10.0%) and rash(6.7%).Only 11 cases(36.7%) had the typical abortus fever.Blood routine and liver functions were normal in most patients,while ESR was increased in 23 cases(76.7%),and osteoarthropathy was comfirmed by radiograph in 8 cases(36.4%).Only 2 cases were confirmed the diagnosis during the first visit.The combinational treatment with Doxycycline,Rifampin and Levofloxacin were effective,with the result that 27 cases had their fever dropped to normal in 2 weeks.Conclusion:Sporadic cases of brucellosis in Xuzhou increas gradually in recent years,which usually have atypical clinical manifestations.Epidemiological clues should be kept in mind in order to avoid misdiagnosis.The combinational therapy of Doxycycline,Rifampin and Levofloxacin are effective against brucellosis.
