实用医院临床杂志
實用醫院臨床雜誌
실용의원림상잡지
PRACTICAL JOURNAL OF CLINICAL MEDICINE
2015年
1期
69-70,71
,共3页
陈岱莉%齐晓非%曹君%黄晓雷%李元涛
陳岱莉%齊曉非%曹君%黃曉雷%李元濤
진대리%제효비%조군%황효뢰%리원도
氟比洛芬酯%地塞米松%昂丹司琼%超前镇痛%妇科腹腔镜术
氟比洛芬酯%地塞米鬆%昂丹司瓊%超前鎮痛%婦科腹腔鏡術
불비락분지%지새미송%앙단사경%초전진통%부과복강경술
Flurbiprofen axetil%Dexamethasone%Ondansetron%Preemptive analgesia%Gynecological laparoscopic surgery
目的:观察氟比洛芬酯超前镇痛在妇科腹腔镜手术中的应用效果。方法择期腹腔镜下行妇科手术患者52例,ASA I~II,按照随机数字表法分为A组与B组各26例。 A组在麻醉诱导前静脉注射氟比洛芬酯50 mg复合地塞米松10 mg和昂丹司琼4 mg;B组在麻醉诱导前静脉注射相同容量的生理盐水。观察两组苏醒时间以及拔管后即刻、拔管后1、2、3、8 h的收缩压( SBP)、心率( HR)、镇痛评分(视觉模拟评分法,VAS)、镇静评分( Ramsay评分法)和不良反应,记录两组患者术后24 h内追加镇痛药的情况。结果 A组拔管后各时点的VAS评分明显低于B组( P<0.05),恶心呕吐的发生率及术后24 h内追加镇痛药的患者明显少于B组(P<0.05)。两组Ramsay评分、苏醒时间、SBP、HR的变化和不良反应比较差异无统计学意义( P>0.05)。结论氟比洛芬酯超前用于妇科腹腔镜手术,具有良好的镇痛效果,不良反应发生率低,不影响全麻苏醒时间,安全性高。
目的:觀察氟比洛芬酯超前鎮痛在婦科腹腔鏡手術中的應用效果。方法擇期腹腔鏡下行婦科手術患者52例,ASA I~II,按照隨機數字錶法分為A組與B組各26例。 A組在痳醉誘導前靜脈註射氟比洛芬酯50 mg複閤地塞米鬆10 mg和昂丹司瓊4 mg;B組在痳醉誘導前靜脈註射相同容量的生理鹽水。觀察兩組囌醒時間以及拔管後即刻、拔管後1、2、3、8 h的收縮壓( SBP)、心率( HR)、鎮痛評分(視覺模擬評分法,VAS)、鎮靜評分( Ramsay評分法)和不良反應,記錄兩組患者術後24 h內追加鎮痛藥的情況。結果 A組拔管後各時點的VAS評分明顯低于B組( P<0.05),噁心嘔吐的髮生率及術後24 h內追加鎮痛藥的患者明顯少于B組(P<0.05)。兩組Ramsay評分、囌醒時間、SBP、HR的變化和不良反應比較差異無統計學意義( P>0.05)。結論氟比洛芬酯超前用于婦科腹腔鏡手術,具有良好的鎮痛效果,不良反應髮生率低,不影響全痳囌醒時間,安全性高。
목적:관찰불비락분지초전진통재부과복강경수술중적응용효과。방법택기복강경하행부과수술환자52례,ASA I~II,안조수궤수자표법분위A조여B조각26례。 A조재마취유도전정맥주사불비락분지50 mg복합지새미송10 mg화앙단사경4 mg;B조재마취유도전정맥주사상동용량적생리염수。관찰량조소성시간이급발관후즉각、발관후1、2、3、8 h적수축압( SBP)、심솔( HR)、진통평분(시각모의평분법,VAS)、진정평분( Ramsay평분법)화불량반응,기록량조환자술후24 h내추가진통약적정황。결과 A조발관후각시점적VAS평분명현저우B조( P<0.05),악심구토적발생솔급술후24 h내추가진통약적환자명현소우B조(P<0.05)。량조Ramsay평분、소성시간、SBP、HR적변화화불량반응비교차이무통계학의의( P>0.05)。결론불비락분지초전용우부과복강경수술,구유량호적진통효과,불량반응발생솔저,불영향전마소성시간,안전성고。
Objective To observe the effects of preemptive analgesia of flubiprofen axetil in patients undergoing gynecological laparoscopic surgery.Methods Fifty-two adult patients(ASA I~II)scheduled for selective gynecological laparoscopic surgery were randomly divided into A and B groups,26 in each group.Before induction of general anesthesia,patients in the group A received flurbi-profen axetil 50 mg combined with dexamethasone 10 mg and ondansetron 4 mg,while patients in the group B received the equivalent volume of saline.When operation was finished,the awaking time of anesthesia,systolic blood pressure( SBP) ,heart rate( HR) ,the pain score of visual analogue scale( VAS) ,the sedation grades of Ramesay score and incidence of adverse events were recorded at the emer-gence from extubation,1,2,3 and 8 h after extubation.The cases of additonal analgesics were recorded within 24 h after operation.Re-sults At each observation point,the VAS in the group A were significantly lower than that in the group B(P<0.05).The Ramesay scores were similar between the two groups.The incidance of additonal analgesics and nausea and vomiting in the group A were signifi-cantly lower than that in the group B(P<0.05).There was no significant difference in the awaking time of anesthesia,SBP,HR and in-cidence of adverse events between the two groups.Conclusion Preemptive analgesia with flurbiprofen can provide satisfactory pain re-lief with no obvious side effects in gynecological laparoscopic surgery,which also does not affect the awakening time,thus can provide high safety for patients.