CAJ | 학술논문

研究了以溴代异戊烯水解工艺和精馏分离工艺为基础来制备3-甲基-2-丁烯-1-醇的新工艺。通过优化溶剂种类得到当水解溶剂为偶极类溶剂乙腈时，得到产物的选择性最高。并通过进一步优化实验操作条件，得到当溶剂加入量为 v(乙腈)：v(溴代异戊烯)=1∶1，水解温度为70℃，碱用量为 n(NaOH)∶n(溴代异戊烯)=1.2∶1和反应时间为25min时，水解部分3-甲基-2-丁烯-1-醇的转化率最高可达63.35%。水解后的料液通过间歇精馏得到纯的3-甲基-2-丁烯-1-醇，最终的3-甲基-2-丁烯-1-醇总收率达到57.4%。
연구료이추대이무희수해공예화정류분리공예위기출래제비3-갑기-2-정희-1-순적신공예。통과우화용제충류득도당수해용제위우겁류용제을정시，득도산물적선택성최고。병통과진일보우화실험조작조건，득도당용제가입량위 v(을정)：v(추대이무희)=1∶1，수해온도위70℃，감용량위 n(NaOH)∶n(추대이무희)=1.2∶1화반응시간위25min시，수해부분3-갑기-2-정희-1-순적전화솔최고가체63.35%。수해후적료액통과간헐정류득도순적3-갑기-2-정희-1-순，최종적3-갑기-2-정희-1-순총수솔체도57.4%。
A new technology for the preparation of 3-methyl-2-butene-1-ol was investigated based on the hydrolysis of brominated isoamylene and distillation separation technology. By choosing a dipolar solvent,acetonitrile,for the hydrolysis the products showed the highest selectivity. And through further the optimization of experimental operating conditions,hydrolysis yield of 3-methyl-2-butene-1-ol reached 63.35%under the condition of the solvent amount v(acetonitrile)∶v(bromo-3-ene)=1∶1, hydrolysis temperature 70℃,base amount n(NaOH)∶n(bromo-3-ene)=1.2∶1 and reaction time 25 minutes. The pure 3-methyl-2-butene-1-ol was made of the feed liquid after hydrolysis by batch distillation operation,and the final total yield of 3-methyl-2-butene-1-ol reached 54%.