CAJ | 학술논문

目的：调查分析国内慢性荨麻疹临床疗效判断标准。方法：采用频数分析、K－均值聚类分析等方法，分析目前国内慢性荨麻疹相关疗效判断标准的使用情况与适用范围。结果：符合纳入标准的文献857篇，文献中症状评估指标和疗效评价标准各不相同，采用症状体征下降指数（ SSRI）四级分级法的文献549篇（占64．17％）。采用K－均值聚类统计分析后发现，以治愈（100％≥SSRI＞90％）、好转（90％≥SSRI＞60％）、显效（60％≥SSRI＞20％）、无效（20％≥SSRI≥0％）为标准的四级疗效分级法适用范围较广。结论：慢性荨麻疹临床评估和药物疗效判断标准亟待统一和标准化。
목적：조사분석국내만성담마진림상료효판단표준。방법：채용빈수분석、K－균치취류분석등방법，분석목전국내만성담마진상관료효판단표준적사용정황여괄용범위。결과：부합납입표준적문헌857편，문헌중증상평고지표화료효평개표준각불상동，채용증상체정하강지수（ SSRI）사급분급법적문헌549편（점64．17％）。채용K－균치취류통계분석후발현，이치유（100％≥SSRI＞90％）、호전（90％≥SSRI＞60％）、현효（60％≥SSRI＞20％）、무효（20％≥SSRI≥0％）위표준적사급료효분급법괄용범위교엄。결론：만성담마진림상평고화약물료효판단표준극대통일화표준화。
Objective To investigate the criteria for assessing the clinical therapeutic effect of chronic urticaria in China.Methods The application of criteria for assessing the clinical therapeutic effect of chronic urticaria in China and their applicable scope were analyzed by frequency analysis and K-means clustering analysis, respectively.Results The criteria for assessing symptoms and therapeutic effect were different in the 857 papers included in this study. SSRI was used in 549 (64.17) out of the 857 papers included in this study.K-means clustering analysis showed that the applicable scope of SSRI with curative rate ( 100%≥SSRI>90%) , improvement rate ( 90%≥SSR<60%) , Significant effect rate (60%≥SSRI>20%) , and no response rate (20%≥SSR≥0%) as its criteria was wider than that of frequency analysis.Conclusion The criteria for the clinical assessment of chronic urticaria and its drug treatment effect should be unified and standardized.