医学临床研究
醫學臨床研究
의학림상연구
JOURNAL OF CLINICAL RESEARCH
2014年
11期
2095-2097
,共3页
脑梗死/药物疗法%急性病%氧%自由基清除剂
腦梗死/藥物療法%急性病%氧%自由基清除劑
뇌경사/약물요법%급성병%양%자유기청제제
Brain Infarction/DT%Acute Disease%Oxygen%Free Radical Scavengers
目的 探讨依达那奉治疗急性脑梗死的临床疗效。方法 随机选择2012年1月至2013年12月本院收治的64例急性脑梗死患者，所有患者均在发病24 h内到医院诊治。随机将这些患者分为试验组和对照组，每组各32例。对照组常规给予血塞通针静脉滴注；试验组在对照组的基础上给予依达那奉治疗，观察两组的治疗结果。结果 试验组有31例患者治疗有效，1例为无效，有效率为96．9％（31／32）；对照组30例患者治疗有效，2例无效，有效率为93．8％（30／32）。两组的总有效率比较差异无统计学意义；两组治疗后NIHSS评分和Bathel指数均较治疗前有明显的改善（均 P ＜0．05），且试验组明显优于对照组差异有统计学意义（均 P ＜0．05）。结论 在脑梗死早期使用依达那奉治疗，改善神经功能缺损症状，值得临床推广应用。
目的 探討依達那奉治療急性腦梗死的臨床療效。方法 隨機選擇2012年1月至2013年12月本院收治的64例急性腦梗死患者，所有患者均在髮病24 h內到醫院診治。隨機將這些患者分為試驗組和對照組，每組各32例。對照組常規給予血塞通針靜脈滴註；試驗組在對照組的基礎上給予依達那奉治療，觀察兩組的治療結果。結果 試驗組有31例患者治療有效，1例為無效，有效率為96．9％（31／32）；對照組30例患者治療有效，2例無效，有效率為93．8％（30／32）。兩組的總有效率比較差異無統計學意義；兩組治療後NIHSS評分和Bathel指數均較治療前有明顯的改善（均 P ＜0．05），且試驗組明顯優于對照組差異有統計學意義（均 P ＜0．05）。結論 在腦梗死早期使用依達那奉治療，改善神經功能缺損癥狀，值得臨床推廣應用。
목적 탐토의체나봉치료급성뇌경사적림상료효。방법 수궤선택2012년1월지2013년12월본원수치적64례급성뇌경사환자，소유환자균재발병24 h내도의원진치。수궤장저사환자분위시험조화대조조，매조각32례。대조조상규급여혈새통침정맥적주；시험조재대조조적기출상급여의체나봉치료，관찰량조적치료결과。결과 시험조유31례환자치료유효，1례위무효，유효솔위96．9％（31／32）；대조조30례환자치료유효，2례무효，유효솔위93．8％（30／32）。량조적총유효솔비교차이무통계학의의；량조치료후NIHSS평분화Bathel지수균교치료전유명현적개선（균 P ＜0．05），차시험조명현우우대조조차이유통계학의의（균 P ＜0．05）。결론 재뇌경사조기사용의체나봉치료，개선신경공능결손증상，치득림상추엄응용。
Objective] To explore clinical efficacy of edaravone for the treatment of cerebral infarction .[Methods] A total of 64 patients with cerebral infarction in our hospital form Jan .2012 to Dec .2013 were randomly selected .All patients were admitted to the hospital for the diagnosis and treatment within 24h of on‐set .These patients were randomly divided into experimental group( n=32) and control group( n =32) .The control group was given intravenous instillation with conventional Xuesaitong needle ,while the experimental group was given edaravone based on the treatment of control group .The treatment results of two groups were observed .[Results] In experimental group ,31 patients were effective treatment ,and 1 patient was invalid , and the effective rate was 96 .9% (31/32) .In control group ,30 patients were effective treatment ,and 2 pa‐tients were invalid ,and the effective rate was 93 .8% (30/32) .There is no significant difference in the total ef‐fective rate between two groups .Compared with before treatment ,NIHSS score and Bathel index of two groups after treatment were obviously improved(all P<0 .05) ,and those in experimental group were obvious‐ly better than the control group ,and there was significant difference(all P<0 .05) .[Conclusion]Edaravone for early treatment of cerebral infarction can improve the symptoms of neurologic impairment .Therefore ,it is worthy of clinical promotion .
