CAJ | 학술논문

目的：观察盐酸倍他司汀注射液联合盐酸利多卡因注射液及葛根素注射液治疗椎-基底动脉供血不足的临床疗效。方法：将椎-基底动脉供血不足患者132例随机分为2组，治疗组68例予盐酸利多卡因注射液0.1 g加入盐酸倍他司汀注射液500 mL内静脉滴注，1次/d，共7天，葛根素注射液0.4 g加入生理盐水250 mL内静脉滴注，1次/d，共14天；对照组64例予敏使朗6 mg，3次/d，盐酸氟桂利嗪10 mg，1次/d，每晚口服，盐酸丁咯地尔0.2 g加入生理盐水250 mL内静脉滴注，1次/d，共14天。观察2组患者临床疗效及椎-基底动脉血液流速变化情况。结果：治疗组和对照组总有效率分别为92.65%、76.56%，治疗组总有效率优于对照组(P＜0.05)；治疗组椎-基底动脉血液流速改善优于对照组(P＜0.05)。结论：盐酸倍他司汀注射液与盐酸利多卡因注射液、葛根素注射液联合应用是椎-基底动脉供血不足患者的有效治疗方法。
목적：관찰염산배타사정주사액연합염산리다잡인주사액급갈근소주사액치료추-기저동맥공혈불족적림상료효。방법：장추-기저동맥공혈불족환자132례수궤분위2조，치료조68례여염산리다잡인주사액0.1 g가입염산배타사정주사액500 mL내정맥적주，1차/d，공7천，갈근소주사액0.4 g가입생리염수250 mL내정맥적주，1차/d，공14천；대조조64례여민사랑6 mg，3차/d，염산불계리진10 mg，1차/d，매만구복，염산정각지이0.2 g가입생리염수250 mL내정맥적주，1차/d，공14천。관찰2조환자림상료효급추-기저동맥혈액류속변화정황。결과：치료조화대조조총유효솔분별위92.65%、76.56%，치료조총유효솔우우대조조(P＜0.05)；치료조추-기저동맥혈액류속개선우우대조조(P＜0.05)。결론：염산배타사정주사액여염산리다잡인주사액、갈근소주사액연합응용시추-기저동맥공혈불족환자적유효치료방법。
Objective:To survey clinical effects of betahistine hydrochloride injection, lidocaine hydrochloride injection and puerarin injection in the treatment for vertebrobasilar insufficiency. Methods:All 132 cases were ran-domized into two groups, 68 cases of the treatment group accepted intravenous dripping of lidocaine hydrochloride injection, 0.1g, added into betahistine hydrochloride injection, 500 mL, once each day, for seven days, puerarin in-jection, 0.4 g, added into physiological saline, 250 mL, oncer per day, for 14 days;64 cases of the control group re-ceived oral administration of betahistine, 6mg, three times each day, and flunarizine hydrochloride, 10mg, once each day, in the evening, buflomedil hydrochloride, 0.2g, added into physiological saline, 250 mL, oncer per day, for 14 days. Curative effects of both groups and the changes of vertebrobasilar blood flow were observed. Results:Total ef-fective rates of the treatment group and the control group were 92.65%and 76.56%respectively, the treatment group was superior to the control group obviously (P<0.05);the treatment group was better than the control group in im-proving vertebrobasilar blood flow. Conclusion: The combination of betahistine hydrochloride injection, lidocaine hydrochloride injection and puerarin injection are effective methods for the patients with vertebrobasilar insufficiency.