CAJ | 학술논문

多糖在自然界中含量丰富，通过糖苷键连接成醛糖或酮糖。多糖是生命活动中重要的营养物质之一，具有许多非常重要且特殊的理化特性和生理活性，如毒性小、较安全、功能多样等。已有研究表明，从植物中提取的水溶性多糖有极其广泛的药理活性，如增强免疫功能、降血糖、调节血脂、抗肿瘤、抗氧化、抗衰老作用等。新近研究发现，人参、枸杞、黄芪、灵芝等水溶性多糖对神经细胞有保护作用。我们简要综述了植物多糖对神经细胞保护作用的研究进展，以期为多糖作为老年神经性疾病的补充与替代治疗药物提供理论依据。
다당재자연계중함량봉부，통과당감건련접성철당혹동당。다당시생명활동중중요적영양물질지일，구유허다비상중요차특수적이화특성화생리활성，여독성소、교안전、공능다양등。이유연구표명，종식물중제취적수용성다당유겁기엄범적약리활성，여증강면역공능、강혈당、조절혈지、항종류、항양화、항쇠로작용등。신근연구발현，인삼、구기、황기、령지등수용성다당대신경세포유보호작용。아문간요종술료식물다당대신경세포보호작용적연구진전，이기위다당작위노년신경성질병적보충여체대치료약물제공이론의거。
Polysaccharide, which is connected into aldose or ketose by glycosidic bond, is rich in the nature. Polysaccharide is one of the important nutrients in life activities and has many important and special physicochemi?cal properties and physiological activities, such as low toxicity, safer and functional diversity, etc. It is well known that water-soluble polysaccharide extracted from plants has a lot of significant pharmacological activities, such as boosting immune function, regulating blood sugar and blood fat levels, anti-tumor, anti-oxidation, anti-aging, etc. Recent studies have found that water-soluble polysaccharides from ginseng, Chinese wolfberry, astragalus and gano?derma lucidum have protective effects on nerve cells. Here, we reviewed the polysaccharide and its protective ef?fects on nerve cells, in order to provide a theoretical basis for the polysaccharides can become complementary and alternative medicine treating senile neurological diseases.