陕西科技大学学报（自然科学版）
陝西科技大學學報（自然科學版）
협서과기대학학보（자연과학판）
JOURNAL OF SHAANXI UNIVERSITY OF SCIENCE & TECHNOLOGY
2015年
1期
62-65,78
,共5页
刘俊莉%王敏%惠爱平
劉俊莉%王敏%惠愛平
류준리%왕민%혜애평
水热合成%碳微球%中空ZnO微球%药物缓释
水熱閤成%碳微毬%中空ZnO微毬%藥物緩釋
수열합성%탄미구%중공ZnO미구%약물완석
hydrothermal synthesis%carbon microspheres%hollow ZnO microspheres%drug release
以碳微球为模板制备中空ZnO微球，接着采用浸渍法将防霉剂填充在中空ZnO微球中，同时对其在水中的缓释效果进行了研究．采用扫描电镜（SEM ）和透射电镜（T EM ）研究了反应时间和葡萄糖浓度对碳微球形貌的影响，以及不同碳微球模板对中空ZnO微球形貌和结构的影响．SEM 和T EM测试结果表明：采用水热法成功地制备了尺寸为50～200 nm的碳微球和40 nm左右的中空ZnO微球．缓释实验结果表明：载药中空ZnO微球从1 h到9 h释放的防霉剂浓度从0．0083mg／mL增加到0．0214mg／mL，缓释效果明显．
以碳微毬為模闆製備中空ZnO微毬，接著採用浸漬法將防黴劑填充在中空ZnO微毬中，同時對其在水中的緩釋效果進行瞭研究．採用掃描電鏡（SEM ）和透射電鏡（T EM ）研究瞭反應時間和葡萄糖濃度對碳微毬形貌的影響，以及不同碳微毬模闆對中空ZnO微毬形貌和結構的影響．SEM 和T EM測試結果錶明：採用水熱法成功地製備瞭呎吋為50～200 nm的碳微毬和40 nm左右的中空ZnO微毬．緩釋實驗結果錶明：載藥中空ZnO微毬從1 h到9 h釋放的防黴劑濃度從0．0083mg／mL增加到0．0214mg／mL，緩釋效果明顯．
이탄미구위모판제비중공ZnO미구，접착채용침지법장방매제전충재중공ZnO미구중，동시대기재수중적완석효과진행료연구．채용소묘전경（SEM ）화투사전경（T EM ）연구료반응시간화포도당농도대탄미구형모적영향，이급불동탄미구모판대중공ZnO미구형모화결구적영향．SEM 화T EM측시결과표명：채용수열법성공지제비료척촌위50～200 nm적탄미구화40 nm좌우적중공ZnO미구．완석실험결과표명：재약중공ZnO미구종1 h도9 h석방적방매제농도종0．0083mg／mL증가도0．0214mg／mL，완석효과명현．
The carbon microspheres were used as the template in the preparation of hollow ZnO microspheres .Then mildew proof agent was filled in the hollow ZnO microspheres by dipping method ,and its slow‐release effect in water was discussed .The effect of the different reaction times ,the concentrations of glucose and carbon microspheres on the morphology of hollow ZnO microspheres were investigated by field emission scanning electron microscope (SEM ) and transmission electron microscope (T EM ) .SEM and T EM results show ed that carbon microspheres with the sizes of 50~200 nm and hollow ZnO microsphere with the size of 40 nm were prepared successfully .The concentration of mildew proof agent in hollow ZnO microspheres was released from 0 .008 3 mg/mL to 0 .021 4 mg/mL from the first hour to the ninth hour ,which showed the better load and slow‐release effect .
